Cholangiocarcinoma: Epidemiology and risk factors

SA Khan, S Tavolari, G Brandi - Liver International, 2019‏ - Wiley Online Library
Cholangiocarcinoma (CCA) is a heterogeneous disease arising from a complex interaction
between host‐specific genetic background and multiple risk factors. Globally, CCA …

Haemochromatosis

P Brissot, A Pietrangelo, PC Adams… - Nature reviews Disease …, 2018‏ - nature.com
Haemochromatosis is defined as systemic iron overload of genetic origin, caused by a
reduction in the concentration of the iron regulatory hormone hepcidin, or a reduction in …

Hemochromatosis classification: update and recommendations by the BIOIRON Society

D Girelli, F Busti, P Brissot, I Cabantchik… - Blood, The Journal …, 2022‏ - ashpublications.org
Hemochromatosis (HC) is a genetically heterogeneous disorder in which uncontrolled
intestinal iron absorption may lead to progressive iron overload (IO) responsible for …

[HTML][HTML] Biomarkers of Nutrition for Development (BOND)—iron review

S Lynch, CM Pfeiffer, MK Georgieff, G Brittenham… - The Journal of …, 2018‏ - Elsevier
This is the fifth in the series of reviews developed as part of the Biomarkers of Nutrition for
Development (BOND) program. The BOND Iron Expert Panel (I-EP) reviewed the extant …

Iron overload, oxidative stress, and ferroptosis in the failing heart and liver

D Mancardi, M Mezzanotte, E Arrigo, A Barinotti… - Antioxidants, 2021‏ - mdpi.com
Iron accumulation is a key mediator of several cytotoxic mechanisms leading to the
impairment of redox homeostasis and cellular death. Iron overload is often associated with …

ACG clinical guideline: hereditary hemochromatosis

KV Kowdley, KE Brown, J Ahn… - Official journal of the …, 2019‏ - journals.lww.com
Hereditary hemochromatosis (HH) is one of the most common genetic disorders among
persons of northern European descent. There have been recent advances in the diagnosis …

Hemochromatosis

JK Olynyk, GA Ramm - New England Journal of Medicine, 2022‏ - Mass Medical Soc
Hemochromatosis | New England Journal of Medicine Skip to main content The New England
Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology Clinical …

[HTML][HTML] The regulation of iron absorption and homeostasis

DF Wallace - The Clinical Biochemist Reviews, 2016‏ - ncbi.nlm.nih.gov
Iron is an essential element in biology, required for numerous cellular processes. Either too
much or too little iron can be detrimental, and organisms have developed mechanisms for …

[PDF][PDF] Diagnosis and management of hemochromatosis: 2011 practice guideline by the American Association for the Study of Liver Diseases

BR Bacon, PC Adams, KV Kowdley, LW Powell… - …, 2011‏ - Wiley Online Library
To more fully characterize the available evidence supporting the recommendations, the
AASLD Practice Guidelines Committee has adopted the classification used by the Grading …

Hyperferritinemia—a clinical overview

M Sandnes, RJ Ulvik, M Vorland… - Journal of Clinical …, 2021‏ - mdpi.com
Ferritin is one of the most frequently requested laboratory tests in primary and secondary
care, and levels often deviate from reference ranges. Serving as an indirect marker for total …