The transient receptor potential ankyrin (TRPA) channels are Ca 2+-permeable nonselective
cation channels remarkably conserved through the animal kingdom. Mammals have only …

Ciguatera Fish Poisoning (CFP) is the most frequently reported seafood-toxin illness in the
world. It causes substantial human health, social, and economic impacts. The illness …

Nociception is an important physiological process that detects harmful signals and results in
pain perception. In this review, we discuss important experimental evidence involving some …

Our ability to perceive temperature is crucial: it enables us to swiftly react to noxiously cold or
hot objects and helps us to maintain a constant body temperature. Sensory nerve endings …

Transient receptor potential (TRP) channels are important mediators of sensory signals with
marked effects on cellular functions and signalling pathways. Indeed, mutations in genes …

Venomous animals have evolved toxins that interfere with specific components of their
victim's core physiological systems, thereby causing biological dysfunction that aids in prey …

While considerable effort has been made to investigate the neural mechanisms of pain,
much less effort has been devoted to itch, at least until recently. However, itch is now gaining …

The transient receptor potential ankyrin subtype 1 protein (TRPA1) is a nonselective cation
channel permeable to Ca 2+, Na+, and K+. TRPA1 is a promiscuous chemical nocisensor …

TRPA1 is a non‐selective cation channel expressed in mammalian peripheral pain
receptors, with a major role in chemonociception. TRPA1 has also been implicated in …

Noxious stimuli usually cause pain and pain usually arises from noxious stimuli, but
exceptions to these apparent truisms are the basis for clinically important problems and …