HIV transmission

GM Shaw, E Hunter - Cold Spring Harbor …, 2012 - perspectivesinmedicine.cshlp.org
HIV-1 is transmitted by sexual contact across mucosal surfaces, by maternal-infant
exposure, and by percutaneous inoculation. For reasons that are still incompletely …

Evolutionary and immunological implications of contemporary HIV-1 variation

B Korber, B Gaschen, K Yusim… - British medical …, 2001 - academic.oup.com
Evolutionary modelling studies indicate less than a century has passed since the most
recent common ancestor of the HIV-1 pandemic strains and, in that time frame, an …

Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection

JF Salazar-Gonzalez, MG Salazar, BF Keele… - Journal of Experimental …, 2009 - rupress.org
Identification of full-length transmitted HIV-1 genomes could be instrumental in HIV-1
pathogenesis, microbicide, and vaccine research by enabling the direct analysis of those …

Absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection

F Kirchhoff, TC Greenough, DB Brettler… - … England Journal of …, 1995 - Mass Medical Soc
Although disease develops within 10 years in most persons infected with human
immunodeficiency virus type 1 (HIV-1), some remain symptom-free for prolonged periods. 1 …

The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells.

NK Heinzinger, MI Bukinsky, SA Haggerty… - Proceedings of the …, 1994 - pnas.org
The replication of human immunodeficiency virus type 1 (HIV-1) in nondividing host cells
such as those of macrophage lineage is an important feature of AIDS pathogenesis. The …

Genotypic and phenotypic characterization of HIV-1 patients with primary infection

T Zhu, H Mo, N Wang, DS Nam, Y Cao, RA Koup… - Science, 1993 - science.org
Better characterization of human immunodeficiency virus-type 1 (HIV-1) in patients with
primary infection has important implications for the development of an acquired …

[KÖNYV][B] The evolution and emergence of RNA viruses

EC Holmes - 2009 - books.google.com
RNA viruses provide unique insights into the patterns and processes of evolutionary change
in real time. The study of viral evolution is especially topical given the growing awareness …

[KÖNYV][B] HIV and the pathogenesis of AIDS.

JA Levy - 1994 - cabidigitallibrary.org
This book grew out of a scientific review, originally published in Microbiological Reviews. It
has been updated and expanded-now citing more than 2100 references (100 pages of the …

Deciphering human immunodeficiency virus type 1 transmission and early envelope diversification by single-genome amplification and sequencing

JF Salazar-Gonzalez, E Bailes, KT Pham… - Journal of …, 2008 - journals.asm.org
Accurate identification of the transmitted virus and sequences evolving from it could be
instrumental in elucidating the transmission of human immunodeficiency virus type 1 (HIV-1) …

Inhibiting sexual transmission of HIV-1 infection

RJ Shattock, JP Moore - Nature Reviews Microbiology, 2003 - nature.com
The worldwide infection rate for HIV-1 is estimated to be 14,000 per day, but only now, more
than 20 years into the epidemic, are the immediate events between exposure to infectious …