Poly (lactic acid)-based microparticles for drug delivery applications: An overview of recent advances

A Vlachopoulos, G Karlioti, E Balla, V Daniilidis… - Pharmaceutics, 2022 - mdpi.com
The sustained release of pharmaceutical substances remains the most convenient way of
drug delivery. Hence, a great variety of reports can be traced in the open literature …

Recent advances in the formulation of PLGA microparticles for controlled drug delivery

E Lagreca, V Onesto, C Di Natale, S La Manna… - Progress in …, 2020 - Springer
Polymeric microparticles (MPs) are recognized as very popular carriers to increase the
bioavailability and bio-distribution of both lipophilic and hydrophilic drugs. Among different …

[HTML][HTML] Hydrogel-enabled, local administration and combinatorial delivery of immunotherapies for cancer treatment

A Erfani, AE Diaz, PS Doyle - Materials Today, 2023 - Elsevier
Throughout the last decade, interventions to engineer the immune system called
immunotherapy have revolutionized the fields of oncology and autoimmune disease …

Chitosan and its derivatives for ocular delivery formulations: Recent advances and developments

A Zamboulis, S Nanaki, G Michailidou, I Koumentakou… - Polymers, 2020 - mdpi.com
Chitosan (CS) is a hemi-synthetic cationic linear polysaccharide produced by the
deacetylation of chitin. CS is non-toxic, highly biocompatible, and biodegradable, and it has …

Nanotechnology for topical drug delivery to the anterior segment of the eye

A Vaneev, V Tikhomirova, N Chesnokova… - International journal of …, 2021 - mdpi.com
Topical drug delivery is one of the most challenging aspects of eye therapy. Eye drops are
the most prevalent drug form, especially for widely distributed anterior segment eye …

Chitosan-coated PLGA nanoparticles encapsulating triamcinolone acetonide as a potential candidate for sustained ocular drug delivery

M Dandamudi, P McLoughlin, G Behl, S Rani, L Coffey… - Pharmaceutics, 2021 - mdpi.com
The current treatment for the acquired retinal vasculopathies involves lifelong repeated
intravitreal injections of either anti-vascular endothelial growth factor (VEGF) therapy or …

[HTML][HTML] Microneedle-based ocular drug delivery systems–recent advances and challenges

P Gadziński, A Froelich, M Wojtyłko… - Beilstein Journal of …, 2022 - beilstein-journals.org
Eye diseases and injuries constitute a significant clinical problem worldwide. Safe and
effective delivery of drugs to the eye is challenging mostly due to the presence of ocular …

An overview of gastrointestinal mucus rheology under different pH conditions and introduction to pH-dependent rheological interactions with PLGA and chitosan …

G Ruiz-Pulido, DI Medina - European Journal of Pharmaceutics and …, 2021 - Elsevier
This review discusses the physicochemical and mechanical properties of porcine
gastrointestinal mucus from a rheological point of view. Considering mucus as a viscoelastic …

[HTML][HTML] All-small-molecule supramolecular hydrogels assembled from guanosine 5′-monophosphate disodium salt and tobramycin for the treatment of bacterial …

X Cheng, H Chen, F Yang, J Hong, Y Cheng, J Hu - Bioactive Materials, 2022 - Elsevier
Bacterial keratitis is the most common corneal infection which may lead to blindness, and
seriously threatened the human visual health worldwide. Clinical treatment with antibiotic …

Microscale characterization of abiotic surfaces and prediction of their biofouling/anti-biofouling potential using the AFM colloidal probe technique

A Eskhan, D Johnson - Advances in Colloid and Interface Science, 2022 - Elsevier
Given its detrimental consequences, biofouling is a central problem in industrial applications
that affects submerged artificial abiotic surfaces. For instance, it shortens the service life of …