SARS-CoV-2 infection triggers auto-immune response in ARDS

P Juanes-Velasco, A Landeira-Viñuela… - Frontiers in …, 2022 - frontiersin.org
Acute respiratory distress syndrome (ARDS) is a severe pulmonary disease, which is one of
the major complications in COVID-19 patients. Dysregulation of the immune system and …

Enhancement of tumor cell immunogenicity and antitumor properties derived from platinum-conjugated iron nanoparticles

ÁP Hernández, L Iglesias-Anciones… - Cancers, 2023 - mdpi.com
Simple Summary The immune system has been shown to play a critical role in controlling
tumor development. Therefore, therapeutic strategies based on targeting tumors from this …

Exploring high-throughput immunoassays for biomarker validation in rheumatic diseases in the context of the human Proteome project

M Fuentes, C Ruiz-Romero, S Misiego… - Journal of Proteome …, 2022 - ACS Publications
Rheumatic diseases are high prevalence pathologies with different etiology and evolution
and low sensitivity in clinical diagnosis. Therefore, it is necessary to develop an early …

Assessment of Humoral Response at SARS-CoV-2 Infection by Multipronged Functional Proteomics Approaches

P Juanes-Velasco, JC Pérez-Arévalo… - Journal of Proteome …, 2025 - ACS Publications
In the past decade, a major goal in biomedical research has been to understand why
individuals differ in disease susceptibility, disease dynamics, and progression. In many …

Podophyllic Aldehyde, a Podophyllotoxin Derivate, Elicits Different Cell Cycle Profiles Depending on the Tumor Cell Line: A Systematic Proteomic Analysis

ÁP Hernández, L Chaparro-González… - International Journal of …, 2024 - mdpi.com
When new antitumor therapy drugs are discovered, it is essential to address new target
molecules from the point of view of chemical structure and to carry out efficient and …

Systematic evaluation of plasma signaling cascades by functional proteomics approaches: SARS‐CoV‐2 infection as model

P Juanes‐Velasco, ML García‐Vaquero… - PROTEOMICS …, 2022 - Wiley Online Library
Abstract Purpose Acute phase reactants (APRs) play a critical role in inflammation. The
difference in their physiological functions or the different dynamic ranges of these proteins in …

Functional proteomics based on protein microarray technology for biomedical research

P Juanes-Velasco, C Arias-Hidalgo… - Advances in Protein …, 2024 - Elsevier
This chapter traces a route through Proteomics from its origins to the present day. The
different proteomics applications are discussed with a focus on microarray technology …