Endothelial dysfunction and hypertension

D Konukoglu, H Uzun - Hypertension: from basic research to clinical …, 2017 - Springer
In the past, endothelium was thought to be only a mechanical barrier. Today, endothelium is
known to be a tissue regulating vascular tone, cell growth and the interaction between the …

[HTML][HTML] Endothelial dysfunction and its relation in different disorders: Recent update

A Ray, KC Maharana, S Meenakshi, S Singh - Health Sciences Review, 2023 - Elsevier
Endothelial dysfunction is characterized by a reduction in nitric oxide generation or an
unbalanced distribution of the relaxing and contracting pressures produced by endothelial …

Antiseptic mouthwash, the nitrate–nitrite–nitric oxide pathway, and hospital mortality: a hypothesis generating review

S Blot - Intensive Care Medicine, 2021 - Springer
Meta-analyses and several large cohort studies have demonstrated that antiseptic
mouthwashes are associated with mortality in hospitalized patients. A clear pathogenic …

The amino acid homoarginine inhibits atherogenesis by modulating T-cell function

K Nitz, M Lacy, M Bianchini, K Wichapong… - Circulation …, 2022 - Am Heart Assoc
Background: Amino acid metabolism is crucial for inflammatory processes during
atherogenesis. The endogenous amino acid homoarginine is a robust biomarker for …

Functional implications of vascular endothelium in regulation of endothelial nitric oxide synthesis to control blood pressure and cardiac functions

G Kumar, SK Dey, S Kundu - Life sciences, 2020 - Elsevier
The endothelium is the innermost vascular lining performing significant roles all over the
human body while maintaining the blood pressure at physiological levels. Malfunction of …

Safety of dietary supplementation with arginine in adult humans

CJ McNeal, CJ Meininger, CD Wilborn, CD Tekwe… - Amino acids, 2018 - Springer
Previous studies with animals and humans have shown beneficial effects of dietary
supplementation with l-arginine (Arg) on reducing white fat and improving health. At present …

Reduced endothelial function in myalgic encephalomyelitis/chronic fatigue syndrome–results from open-label cyclophosphamide intervention study

K Sørland, MK Sandvik, IG Rekeland, L Ribu… - Frontiers in …, 2021 - frontiersin.org
Introduction: Patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)
present with a range of symptoms including post-exertional malaise (PEM), orthostatic …

Homoarginine, arginine, and relatives: analysis, metabolism, transport, physiology, and pathology

D Tsikas, G Wu - Amino Acids, 2015 - Springer
The year 2008 witnessed the first report on the increase in the concentration of l-
homoarginine (hArg) in the maternal plasma during human pregnancy. This observation …

Non-canonical amino acids in analyses of protease structure and function

P Goettig, NG Koch, N Budisa - International Journal of Molecular …, 2023 - mdpi.com
All known organisms encode 20 canonical amino acids by base triplets in the genetic code.
The cellular translational machinery produces proteins consisting mainly of these amino …

Is homoarginine a protective cardiovascular risk factor?

ES Karetnikova, N Jarzebska, AG Markov… - … , and vascular biology, 2019 - Am Heart Assoc
A series of recent epidemiological studies have implicated the endogenous
nonproteinogenic amino acid l-homoarginine as a novel candidate cardiovascular risk …