Abstract Organs-on-chips (OoCs) are systems containing engineered or natural miniature
tissues grown inside microfluidic chips. To better mimic human physiology, the chips are …

The extracellular matrix (ECM) has pleiotropic effects, ranging from cell adhesion to cell
survival. In tissue engineering, the use of ECM and ECM-like scaffolds has separated the …

Hydrogels based on photocrosslinkable Hyaluronic Acid Methacrylate (HAMA) and
Chondroitin Sulfate Methacrylate (CSMA) are presently under investigation for tissue …

Research in cell biology greatly relies on cell-based in vitro assays and models that facilitate
the investigation and understanding of specific biological events and processes under …

The study investigated whether both the osteogenic and angiogenic potential of Exos
(Exosomes) can be enhanced by overexpression of exosomal miRNA (microRNA) and to …

Diabetic foot ulcer has become a worldwide clinical medical challenge as traditional
treatments are not effective enough to reduce the amputation rate. Therefore, it is of great …

Aims Naturally secreted extracellular vesicles (EVs) play important roles in stem-mediated
cardioprotection. This study aimed to investigate the cardioprotective function and …

The development of new therapeutic approaches to treat type 1 diabetes mellitus (T1D)
relies on the precise understanding and deciphering of insulin-secreting β-cell biology, as …

Cancer cells rely on glycolysis to support a high proliferation rate. Metformin (Met) is a
promising drug for tumor treatment that targets hexokinase 2 (HK2) to block the glycolytic …

Muscular diseases and injuries are challenging issues in human medicine, resulting in
physical disability. The advent of tissue engineering approaches has paved the way for the …