Advances in the development of new biomarkers for Alzheimer's disease
TO Klyucherev, P Olszewski, AA Shalimova… - Translational …, 2022 - Springer
Alzheimer's disease (AD) is a complex, heterogeneous, progressive disease and is the most
common type of neurodegenerative dementia. The prevalence of AD is expected to increase …
common type of neurodegenerative dementia. The prevalence of AD is expected to increase …
Decreased serum brain-derived neurotrophic factor (BDNF) levels in patients with Alzheimer's disease (AD): a systematic review and meta-analysis
Findings from previous studies reporting the levels of serum brain-derived neurotrophic
factor (BDNF) in patients with Alzheimer's disease (AD) and individuals with mild cognitive …
factor (BDNF) in patients with Alzheimer's disease (AD) and individuals with mild cognitive …
Epigenetics of Alzheimer's disease
There are currently no validated biomarkers which can be used to accurately diagnose
Alzheimer's disease (AD) or to distinguish it from other dementia-causing neuropathologies …
Alzheimer's disease (AD) or to distinguish it from other dementia-causing neuropathologies …
The relation of the brain-derived neurotrophic factor with microRNAs in neurodegenerative diseases and ischemic stroke
Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophin family of growth
factors that plays a crucial role in the development of the nervous system while supporting …
factors that plays a crucial role in the development of the nervous system while supporting …
Antisense oligonucleotides: translation from mouse models to human neurodegenerative diseases
KM Schoch, TM Miller - Neuron, 2017 - cell.com
Multiple neurodegenerative diseases are characterized by single-protein dysfunction and
aggregation. Treatment strategies for these diseases have often targeted downstream …
aggregation. Treatment strategies for these diseases have often targeted downstream …
Unraveling the role of miRNAs in the diagnosis, progression, and therapeutic intervention of Alzheimer's disease
Alzheimer's disease (AD) is a multifaceted, advancing neurodegenerative illness that is
responsible for most cases of neurological impairment and dementia in the aged population …
responsible for most cases of neurological impairment and dementia in the aged population …
The human BDNF gene: peripheral gene expression and protein levels as biomarkers for psychiatric disorders
A Cattaneo, N Cattane, V Begni, CM Pariante… - Translational …, 2016 - nature.com
Brain-derived neurotrophic factor (BDNF) regulates the survival and growth of neurons, and
influences synaptic efficiency and plasticity. The human BDNF gene consists of 11 exons …
influences synaptic efficiency and plasticity. The human BDNF gene consists of 11 exons …
Micro RNA‐125b induces tau hyperphosphorylation and cognitive deficits in Alzheimer's disease
J Banzhaf‐Strathmann, E Benito, S May… - The EMBO …, 2014 - embopress.org
Sporadic Alzheimer's disease (AD) is the most prevalent form of dementia, but no clear
disease‐initiating mechanism is known. Aβ deposits and neuronal tangles composed of …
disease‐initiating mechanism is known. Aβ deposits and neuronal tangles composed of …
Role of miRNAs in neurodegeneration: From disease cause to tools of biomarker discovery and therapeutics
B Roy, E Lee, T Li, M Rampersaud - Genes, 2022 - mdpi.com
Neurodegenerative diseases originate from neuronal loss in the central nervous system
(CNS). These debilitating diseases progress with age and have become common due to an …
(CNS). These debilitating diseases progress with age and have become common due to an …
[HTML][HTML] Epigenetics of childhood trauma: Long term sequelae and potential for treatment
KM Thumfart, A Jawaid, K Bright, M Flachsmann… - Neuroscience & …, 2022 - Elsevier
Childhood trauma (CT) can have persistent effects on the brain and is one of the major risk
factors for neuropsychiatric diseases in adulthood. Recent advances in the field of …
factors for neuropsychiatric diseases in adulthood. Recent advances in the field of …