Expanding plastics recycling technologies: chemical aspects, technology status and challenges
Less than 10% of the plastics generated globally are recycled, while the rest are incinerated,
accumulated in landfills, or leak into the environment. New technologies are emerging to …
accumulated in landfills, or leak into the environment. New technologies are emerging to …
Mechanism-based design of efficient PET hydrolases
Polyethylene terephthalate (PET) is the most widespread synthetic polyester, having been
utilized in textile fibers and packaging materials for beverages and food, contributing …
utilized in textile fibers and packaging materials for beverages and food, contributing …
Particle size reduction of poly (ethylene terephthalate) increases the rate of enzymatic depolymerization but does not increase the overall conversion extent
Enzymatic depolymerization of poly (ethylene terephthalate)(PET) has emerged as a
potential method for PET recycling, but extensive thermomechanical preprocessing to …
potential method for PET recycling, but extensive thermomechanical preprocessing to …
Computational scoring and experimental evaluation of enzymes generated by neural networks
In recent years, generative protein sequence models have been developed to sample novel
sequences. However, predicting whether generated proteins will fold and function remains …
sequences. However, predicting whether generated proteins will fold and function remains …
Towards synthetic PETtrophy: Engineering Pseudomonas putida for concurrent polyethylene terephthalate (PET) monomer metabolism and PET hydrolase …
Background Biocatalysis offers a promising path for plastic waste management and
valorization, especially for hydrolysable plastics such as polyethylene terephthalate (PET) …
valorization, especially for hydrolysable plastics such as polyethylene terephthalate (PET) …
Protein design using structure-based residue preferences
Recent developments in protein design rely on large neural networks with up to 100s of
millions of parameters, yet it is unclear which residue dependencies are critical for …
millions of parameters, yet it is unclear which residue dependencies are critical for …
A review of cross-disciplinary approaches for the identification of novel industrially relevant plastic-degrading enzymes
The large-scale global use of plastics has led to one of the greatest environmental issues of
the 21st century. The incredible durability of these polymers, whilst beneficial for a wide …
the 21st century. The incredible durability of these polymers, whilst beneficial for a wide …
Towards anchoring evolutionary fitness for protein stability with virtual chemical environment recovery
Z Nie, Y Ma, J Chen, Y Liu, Z Liu, P Yang, F Xu… - bioRxiv, 2024 - biorxiv.org
Protein stability offers valuable insights into protein folding and functionality, making it an
integral component of evolutionary fitness. Previous computational methods possess both …
integral component of evolutionary fitness. Previous computational methods possess both …
Exploration of reconstructed PET hydrolase ancestors by biophysical and computational methods
U Bala - 2023 - uwspace.uwaterloo.ca
Ancestral sequence reconstruction (ASR), originally developed for the study of molecular
evolution, has gained attention as a promising method for protein engineering in the recent …
evolution, has gained attention as a promising method for protein engineering in the recent …