Cell division ends with the physical separation of the two daughter cells, a process known as
cytokinesis. This final event ensures that nuclear and cytoplasmic contents are accurately …

The conserved oligomeric Golgi (COG) complex, a multisubunit tethering complex of the
CATCHR (complexes associated with tethering containing helical rods) family, controls …

Cells don't simply separate at cytokinesis. While furrow contraction critically relies on myosin-
II and F-actin, post-furrowing steps are less understood but involve the constriction of …

Phosphoinositides are low abundant but essential phospholipids in eukaryotic cells and
refer to phosphatidylinositol and its seven polyphospho-derivatives. In this review, we …

Glycosylation is the most common post-translational modification of proteins; it mediates
their correct folding and stability, as well as their transport through the secretory transport …

The plasma membrane of eukaryotic cells is composed of a large number of lipid species
that are laterally segregated into functional domains as well as asymmetrically distributed …

Protein sorting between eukaryotic compartments requires vesicular transport, wherein
tethering provides the first contact between vesicle and target membranes. Here we map …

The highly conserved Golgi phosphoprotein 3 (GOLPH3) protein has been described as a
Phosphatidylinositol 4-phosphate [PI (4) P] effector at the Golgi. GOLPH3 is also known as a …

The decoration of proteins by carbohydrates is essential for eukaryotic life yet
heterogeneous due to a lack of biosynthetic templates. This complex carbohydrate mixture …

Cytokinesis requires a tight coordination between actomyosin ring constriction and new
membrane addition along the ingressing cleavage furrow. However, the molecular …