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Therapeutic potential of ectopic olfactory and taste receptors
Olfactory and taste receptors are expressed primarily in the nasal olfactory epithelium and
gustatory taste bud cells, where they transmit real-time sensory signals to the brain …
gustatory taste bud cells, where they transmit real-time sensory signals to the brain …
A systematic review of the biological mediators of fat taste and smell
Taste and smell play a key role in our ability to perceive foods. Overconsumption of highly
palatable energy-dense foods can lead to increased caloric intake and obesity. Thus there is …
palatable energy-dense foods can lead to increased caloric intake and obesity. Thus there is …
A role for tubular Na+/H+ exchanger NHE3 in the natriuretic effect of the SGLT2 inhibitor empagliflozin
A Onishi, Y Fu, R Patel, M Darshi… - American Journal …, 2020 - journals.physiology.org
Inhibitors of proximal tubular Na+-glucose cotransporter 2 (SGLT2) are natriuretic, and they
lower blood pressure. There are reports that the activities of SGLT2 and Na+-H+ exchanger …
lower blood pressure. There are reports that the activities of SGLT2 and Na+-H+ exchanger …
Adipose tissue lipid metabolism: lipolysis
Highlights•Molecular and cellular signals promoting and inhibiting lipolysis.•Transcriptional
control of lipolysis.•Adipose tissue microenvironment control of lipolysis.•Systemic effects of …
control of lipolysis.•Adipose tissue microenvironment control of lipolysis.•Systemic effects of …
A moth odorant receptor highly expressed in the ovipositor is involved in detecting host-plant volatiles
RT Li, LQ Huang, JF Dong, CZ Wang - Elife, 2020 - elifesciences.org
Antennae are often considered to be the nostrils of insects. Here, we sequenced the
transcriptome of the pheromone gland-ovipositor complex of Helicoverpa assulta and …
transcriptome of the pheromone gland-ovipositor complex of Helicoverpa assulta and …
Platelet olfactory receptor activation limits platelet reactivity and growth of aortic aneurysms
As blood transitions from steady laminar flow (S-flow) in healthy arteries to disturbed flow (D-
flow) in aneurysmal arteries, platelets are subjected to external forces. Biomechanical …
flow) in aneurysmal arteries, platelets are subjected to external forces. Biomechanical …
Olfactory, taste, and photo sensory receptors in non-sensory organs: it just makes sense
Sensory receptors that detect and respond to light, taste, and smell primarily belong to the G-
protein-coupled receptor (GPCR) superfamily. In addition to their established roles in the …
protein-coupled receptor (GPCR) superfamily. In addition to their established roles in the …
[HTML][HTML] Autonomous sensing of the insulin peptide by an olfactory G protein-coupled receptor modulates glucose metabolism
J Cheng, Z Yang, XY Ge, MX Gao, R Meng, X Xu… - Cell Metabolism, 2022 - cell.com
Along with functionally intact insulin, diabetes-associated insulin peptides are secreted by β
cells. By screening the expression and functional characterization of olfactory receptors …
cells. By screening the expression and functional characterization of olfactory receptors …
Odorant receptors in cancer
Odorant receptors (ORs), the largest subfamily of G protein-coupled receptors, detect
odorants in the nose. In addition, ORs were recently shown to be expressed in many …
odorants in the nose. In addition, ORs were recently shown to be expressed in many …
Genome-wide identification of copy number variation and association with fat deposition in thin and fat-tailed sheep breeds
Copy number variants (CNVs) are a type of genetic polymorphism which contribute to
phenotypic variation in several species, including livestock. In this study, we used genomic …
phenotypic variation in several species, including livestock. In this study, we used genomic …