Abstract Iron-sulfur (Fe–S) clusters are essential cofactors most commonly known for their
role mediating electron transfer within the mitochondrial respiratory chain. The Fe–S cluster …

Plasmodium falciparum malaria, an infectious disease caused by a parasitic protozoan,
claims the lives of nearly a million children each year in Africa alone and is a top public …

Plastids (chloroplasts) have long been recognized to have originated by endosymbiosis of a
cyanobacterium, but their subsequent evolutionary history has proved complex because …

Plastids and mitochondria each arose from a single endosymbiotic event and share many
similarities in how they were reduced and integrated with their host. However, the …

Plasmodium spp parasites harbor an unusual plastid organelle called the apicoplast. Due to
its prokaryotic origin and essential function, the apicoplast is a key target for development of …

The human malaria parasite Plasmodium vivax is responsible for 25–40% of the∼ 515
million annual cases of malaria worldwide. Although seldom fatal, the parasite elicits severe …

The ancestors of modern cyanobacteria invented O2-generating photosynthesis some 3.6
billion years ago. The conversion of water and CO2 into energy-rich sugars and O2 slowly …

The ciliate Tetrahymena thermophila is a model organism for molecular and cellular biology.
Like other ciliates, this species has separate germline and soma functions that are …

Plasmodium sporozoites are the product of a complex developmental process in the
mosquito vector and are destined to infect the mammalian liver. Attention has been drawn to …

A comprehensive understanding of the origin and spread of plastids remains an important
yet elusive goal in the field of eukaryotic evolution. Combined with the discovery of new …