Adoptive T-cell therapy using autologous tumor-infiltrating lymphocytes for metastatic melanoma: current status and future outlook
Immunotherapy using autologous T cells has emerged to be a powerful treatment option for
patients with metastatic melanoma. These include the adoptive transfer of autologous tumor …
patients with metastatic melanoma. These include the adoptive transfer of autologous tumor …
CMV infection in hematopoietic stem cell transplantation: prevention and treatment strategies
N Jakharia, D Howard, DJ Riedel - Current treatment options in infectious …, 2021 - Springer
Abstract Purpose of Review Cytomegalovirus (CMV) remains a major cause of morbidity and
mortality after allogeneic hematopoietic stem cell transplantation (Allo-HSCT). New …
mortality after allogeneic hematopoietic stem cell transplantation (Allo-HSCT). New …
[HTML][HTML] Emerging concepts in cytomegalovirus infection following hematopoietic stem cell transplantation
Despite the refinements in molecular methods for the detection of cytomegalovirus (CMV)
and the advent of highly effective preemptive strategies, CMV remains a leading cause of …
and the advent of highly effective preemptive strategies, CMV remains a leading cause of …
Central memory CD4+ T cells dominate the normal cerebrospinal fluid
MT de Graaf, PAES Smitt, RL Luitwieler… - Cytometry Part B …, 2011 - Wiley Online Library
Background: To use cerebrospinal fluid (CSF) immune phenoty** as a diagnostic and
research tool, we have set out to establish reference values of white blood cell (WBC) …
research tool, we have set out to establish reference values of white blood cell (WBC) …
Temporal dynamics of the primary human T cell response to yellow fever virus 17D as it matures from an effector-to a memory-type response
The live attenuated yellow fever virus (YFV) 17D vaccine provides a good model to study
immune responses to an acute viral infection in humans. We studied the temporal dynamics …
immune responses to an acute viral infection in humans. We studied the temporal dynamics …
Deep functional immunophenoty** predicts risk of cytomegalovirus reactivation after hematopoietic cell transplantation
Cytomegalovirus (CMV) is the most common viral infection in hematopoietic cell
transplantation (HCT) recipients. We performed deep phenoty** of CMV-specific T cells to …
transplantation (HCT) recipients. We performed deep phenoty** of CMV-specific T cells to …
Diverse Specificities, Phenotypes, and Antiviral Activities of Cytomegalovirus-Specific CD8+ T Cells
SE Jackson, GM Mason, G Okecha… - Journal of …, 2014 - Am Soc Microbiol
ABSTRACT CD8+ T cells specific for pp65, IE1, and IE2 are present at high frequencies in
human cytomegalovirus (HCMV)-seropositive individuals, and these have been shown to …
human cytomegalovirus (HCMV)-seropositive individuals, and these have been shown to …
CMV exposure drives long-term CD57+ CD4 memory T-cell inflation following allogeneic stem cell transplant
Donor and recipient cytomegalovirus (CMV) serostatus correlate with transplant-related
mortality that is associated with reduced survival following allogeneic stem cell transplant …
mortality that is associated with reduced survival following allogeneic stem cell transplant …
IL-15 induces CD8+ T cells to acquire functional NK receptors capable of modulating cytotoxicity and cytokine secretion
During the last years several authors have described a small population of CD8+ T cells
expressing NK receptors (NKRs). Although their origin remains largely unknown, we have …
expressing NK receptors (NKRs). Although their origin remains largely unknown, we have …
[HTML][HTML] National institutes of health hematopoietic cell transplantation late effects initiative: the immune dysregulation and pathobiology working group report
J Gea-Banacloche, KV Komanduri, P Carpenter… - Biology of blood and …, 2017 - Elsevier
Immune reconstitution after hematopoietic stem cell transplantation (HCT) beyond 1 year is
not completely understood. Many transplant recipients who are free of graft-versus-host …
not completely understood. Many transplant recipients who are free of graft-versus-host …