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Mass spectrometry using electrospray ionization
GRD Prabhu, ER Williams, M Wilm… - Nature Reviews Methods …, 2023 - nature.com
Applying a high voltage to a liquid passing through a capillary disintegrates the liquid
meniscus to generate a fine spray of charged droplets. As the droplets evaporate, polar …
meniscus to generate a fine spray of charged droplets. As the droplets evaporate, polar …
Studies of biomolecular conformations and conformational dynamics by mass spectrometry
Abstract I. Introduction 38 A. Protein Conformations and Dynamics 38 B. Protein‐Energy
Landscapes: The Folding Problem and Dynamics in the Native State 38 1. Protein …
Landscapes: The Folding Problem and Dynamics in the Native State 38 1. Protein …
[HTML][HTML] Electrospray ionization of large multiply charged species proceeds via Dole's charged residue mechanism
JF De La Mora - Analytica chimica acta, 2000 - Elsevier
The maximum charge zmax on a variety of electrospray ions of globular proteins retaining
their native structure, as well as naturally compact starburst dendrimers is compared to the …
their native structure, as well as naturally compact starburst dendrimers is compared to the …
Mechanism of protein aggregation inhibition by arginine: blockage of anionic side chains favors unproductive encounter complexes
Aggregation refers to the assembly of proteins into nonphysiological higher order structures.
While amyloid has been studied extensively, much less is known about amorphous …
While amyloid has been studied extensively, much less is known about amorphous …
Variable-temperature electrospray ionization for temperature-dependent folding/refolding reactions of proteins and ligand binding
Stabilities and structure (s) of proteins are directly coupled to their local environment or
Gibbs free energy landscape as defined by solvent, temperature, pressure, and …
Gibbs free energy landscape as defined by solvent, temperature, pressure, and …
Effects of an electric field on the conformational transition of the protein: a molecular dynamics simulation study
Z Jiang, L You, W Dou, T Sun, P Xu - Polymers, 2019 - mdpi.com
The effect of the electric field on the conformational properties of the protein 1BBL was
investigated by molecular dynamics simulations. Our simulation results clearly capture the …
investigated by molecular dynamics simulations. Our simulation results clearly capture the …
Acid-Induced Unfolding of Cytochrome c at Different Methanol Concentrations: Electrospray Ionization Mass Spectrometry Specifically Monitors Changes in the …
L Konermann, DJ Douglas - Biochemistry, 1997 - ACS Publications
The acid-induced denaturation of ferricytochrome c (cyt c) was examined in aqueous
solutions containing different concentrations of methanol by electrospray ionization mass …
solutions containing different concentrations of methanol by electrospray ionization mass …
Hydrogen/deuterium exchange mass spectrometry with top-down electron capture dissociation for characterizing structural transitions of a 17 kDa protein
Amide H/D exchange (HDX) mass spectrometry (MS) is widely used for protein structural
studies. Traditionally, this technique involves protein labeling in D2O, followed by acid …
studies. Traditionally, this technique involves protein labeling in D2O, followed by acid …
Unfolding of proteins monitored by electrospray ionization mass spectrometry: a comparison of positive and negative ion modes
L Konermann, DJ Douglas - Journal of the American Society for Mass …, 1998 - Springer
Electrospray ionization (ESI) mass spectrometry (MS) in both the positive and negative ion
mode has been used to study protein unfolding transitions of lysozyme, cytochrome c (cyt c) …
mode has been used to study protein unfolding transitions of lysozyme, cytochrome c (cyt c) …
Applications of mass spectrometry to metabolomics and metabonomics: Detection of biomarkers of aging and of age‐related diseases
RJ Mishur, SL Rea - Mass spectrometry reviews, 2012 - Wiley Online Library
Every 5 years or so new technologies, or new combinations of old ones, seemingly burst
onto the science scene and are then sought after until they reach the point of becoming …
onto the science scene and are then sought after until they reach the point of becoming …