Aggregation-induced emission (AIE), life and health

H Wang, Q Li, P Alam, H Bai, V Bhalla, MR Bryce… - ACS …, 2023 - ACS Publications
Light has profoundly impacted modern medicine and healthcare, with numerous
luminescent agents and imaging techniques currently being used to assess health and treat …

Endocytosis in cancer and cancer therapy

B Banushi, SR Joseph, B Lum, JJ Lee… - Nature Reviews …, 2023 - nature.com
Endocytosis is a complex process whereby cell surface proteins, lipids and fluid from the
extracellular environment are packaged, sorted and internalized into cells. Endocytosis is …

Rapid single-particle chemical imaging of nanoplastics by SRS microscopy

N Qian, X Gao, X Lang, H Deng, TM Bratu… - Proceedings of the …, 2024 - pnas.org
Plastics are now omnipresent in our daily lives. The existence of microplastics (1 µm to 5 mm
in length) and possibly even nanoplastics (< 1 μm) has recently raised health concerns. In …

An activatable phototheranostic probe for anti‐hypoxic type I photodynamic‐and immuno‐therapy of cancer

M Zhao, Y Zhang, J Miao, H Zhou, Y Jiang… - Advanced …, 2024 - Wiley Online Library
Photodynamic therapy (PDT), which utilizes type I photoreactions, has great potential as an
effective cancer treatment because of its hypoxia‐tolerant superiority over the commonly …

Nanocarriers address intracellular barriers for efficient drug delivery, overcoming drug resistance, subcellular targeting and controlled release

J Liu, H Cabral, P Mi - Advanced Drug Delivery Reviews, 2024 - Elsevier
The cellular barriers are major bottlenecks for bioactive compounds entering into cells to
accomplish their biological functions, which limits their biomedical applications …

A comparison of cellular uptake mechanisms, delivery efficacy, and intracellular fate between liposomes and extracellular vesicles

TB Gandek, L van der Koog… - Advanced healthcare …, 2023 - Wiley Online Library
A key aspect for successful drug delivery via lipid‐based nanoparticles is their
internalization in target cells. Two prominent examples of such drug delivery systems are …

Dacarbazine-primed carbon quantum dots coated with breast cancer cell-derived exosomes for improved breast cancer therapy

P Tiwari, RP Shukla, K Yadav, N Singh… - Journal of Controlled …, 2024 - Elsevier
Imprecise targeting of chemotherapeutic drugs often leads to severe toxicity during breast
cancer therapy. To address this issue, we have devised a strategy to load dacarbazine (DC) …

Emerging ultrasmall luminescent nanoprobes for in vivo bioimaging

S Li, J Wei, Q Yao, X Song, J **e, H Yang - Chemical Society Reviews, 2023 - pubs.rsc.org
Photoluminescence (PL) imaging has become a fundamental tool in disease diagnosis,
therapeutic evaluation, and surgical navigation applications. However, it remains a big …

Technology insight: Plant-derived vesicles—How far from the clinical biotherapeutics and therapeutic drug carriers?

M Cong, S Tan, S Li, L Gao, L Huang, HG Zhang… - Advanced Drug Delivery …, 2022 - Elsevier
Within the past decades, extracellular vesicles (EVs) have emerged as important mediators
of intercellular communication in both prokaryotes and higher eukaryotes to regulate a …

Carbon dot therapeutic platforms: administration, distribution, metabolism, excretion, toxicity, and therapeutic potential

A Truskewycz, H Yin, N Halberg, DTH Lai, AS Ball… - Small, 2022 - Wiley Online Library
Ultrasmall nanoparticles are often grouped under the broad umbrella term of “nanoparticles”
when reported in the literature. However, for biomedical applications, their small sizes give …