Emerging literature suggests that diet constituents may play a modulatory role in chronic
pain (CP) through management of inflammation/oxidative stress, resulting in attenuation of …

There are significant concerns regarding prescription and misuse of prescription opioids in
the perioperative period. The Faculty of Pain Medicine at the Royal College of Anaesthetists …

Daily use of opioid analgesics has significantly increased in recent years due to an
increasing prevalence of conditions associated with chronic pain. Opioid-induced …

Health care providers in the United States are facing challenges in selecting appropriate
medication for patients with acute and chronic pain in the midst of the current opioid crisis …

Introduction The growing evidence of the increased frequency and severity of adverse drug
events (ADEs), besides the negative impact on patient's health status, indicates that costs …

Introduction Opioid-induced constipation (OIC) is common in people treated with opioids
and poses risks for physical sequelae, analgesic discontinuation, and decreased quality of …

Introduction Laxatives are commonly used to treat opioid-induced constipation, the
commonest and most bothersome complication of opioids. However, laxatives have a …

Constipation is a common and often debilitating condition in the elderly, which may be
caused by underlying disease conditions, structural abnormalities in the bowel, and a variety …

Objective: The objective of this study was to provide an overview of opioid-induced
constipation (OIC) and its influence on disease burden and quality of life (QOL). Methods …

Opioid medications are some of the most commonly prescribed medications for acute and
chronic pain in the United States. In 2016, nearly 92 million US adults, or approximately 38 …