The role of cigarette smoke-induced epigenetic alterations in inflammation
D Zong, X Liu, J Li, R Ouyang, P Chen - Epigenetics & Chromatin, 2019 - Springer
Background Exposure to cigarette smoke (CS) is a major threat to human health worldwide.
It is well established that smoking increases the risk of respiratory diseases, cardiovascular …
It is well established that smoking increases the risk of respiratory diseases, cardiovascular …
DNA methylation changes of whole blood cells in response to active smoking exposure in adults: a systematic review of DNA methylation studies
X Gao, M Jia, Y Zhang, LP Breitling, H Brenner - Clinical epigenetics, 2015 - Springer
Active smoking is a major preventable public health problem and an established critical
factor for epigenetic modification. In this systematic review, we identified 17 studies …
factor for epigenetic modification. In this systematic review, we identified 17 studies …
DNA methylation in newborns and maternal smoking in pregnancy: genome-wide consortium meta-analysis
Epigenetic modifications, including DNA methylation, represent a potential mechanism for
environmental impacts on human disease. Maternal smoking in pregnancy remains an …
environmental impacts on human disease. Maternal smoking in pregnancy remains an …
Guidance for DNA methylation studies: statistical insights from the Illumina EPIC array
Background There has been a steady increase in the number of studies aiming to identify
DNA methylation differences associated with complex phenotypes. Many of the challenges …
DNA methylation differences associated with complex phenotypes. Many of the challenges …
Tobacco smoking-associated genome-wide DNA methylation changes in the EPIC study
Aim: Epigenetic changes may occur in response to environmental stressors, and an altered
epigenome pattern may represent a stable signature of environmental exposure. Materials & …
epigenome pattern may represent a stable signature of environmental exposure. Materials & …
DNA methylation-based age prediction using massively parallel sequencing data and multiple machine learning models
The field of DNA intelligence focuses on retrieving information from DNA evidence that can
help narrow down large groups of suspects or define target groups of interest. With recent …
help narrow down large groups of suspects or define target groups of interest. With recent …
Epigenetic associations of type 2 diabetes and BMI in an Arab population
Background The prevalence of type 2 diabetes (T2D) and obesity has dramatically
increased within a few generations, reaching epidemic levels. In addition to genetic risk …
increased within a few generations, reaching epidemic levels. In addition to genetic risk …
Autosomal sex-associated co-methylated regions predict biological sex from DNA methylation
Sex is a modulator of health that has been historically overlooked in biomedical research.
Recognizing this knowledge gap, funding agencies now mandate the inclusion of sex as a …
Recognizing this knowledge gap, funding agencies now mandate the inclusion of sex as a …
A systematic review of smoking-related epigenetic alterations
The aim of this study is to provide a systematic review of the known epigenetic alterations
caused by cigarette smoke; establish an evidence-based perspective of their clinical value …
caused by cigarette smoke; establish an evidence-based perspective of their clinical value …
Novel age-associated DNA methylation changes and epigenetic age acceleration in middle-aged African Americans and whites
Abstract Background African Americans (AAs) experience premature chronic health
outcomes and longevity disparities consistent with an accelerated aging phenotype. DNA …
outcomes and longevity disparities consistent with an accelerated aging phenotype. DNA …