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The SH-SY5Y human neuroblastoma cell line, a relevant in vitro cell model for investigating neurotoxicology in human: Focus on organic pollutants
L Lopez-Suarez, S Al Awabdh, X Coumoul, C Chauvet - Neurotoxicology, 2022 - Elsevier
Investigation of the toxicity triggered by chemicals on the human brain has traditionally relied
on approaches using rodent in vivo models and in vitro cell models including primary …
on approaches using rodent in vivo models and in vitro cell models including primary …
Resveratrol and brain mitochondria: a review
Abstract Resveratrol (3, 4', 5-trihydroxystilbene; C 14 H 12 O 3) is a polyphenolic phytoalexin
found in grapes, berries, peanuts, and wines. Resveratrol has been viewed as an …
found in grapes, berries, peanuts, and wines. Resveratrol has been viewed as an …
Neuroprotective effects of carnosic acid: Insight into its mechanisms of action
Carnosic acid is a diterpenoid abundantly present in plants belonging to the genus
Rosmarinus and Salvia of the family Lamiaceae, accounting for their application in …
Rosmarinus and Salvia of the family Lamiaceae, accounting for their application in …
Neuroprotective potential of aromatic herbs: rosemary, sage, and lavender
Hundreds of millions of people around the world suffer from neurological disorders or have
experienced them intermittently, which has significantly reduced their quality of life. The …
experienced them intermittently, which has significantly reduced their quality of life. The …
Chlorpyrifos activates cell pyroptosis and increases susceptibility on oxidative stress‐induced toxicity by miR‐181/SIRT1/PGC‐1α/Nrf2 signaling pathway in human …
MW Zhao, P Yang, LL Zhao - Environmental toxicology, 2019 - Wiley Online Library
Background The insecticide exposure has been linked to Parkinson's disease (PD). In the
present study, we used a most widely used cell line in study of PD, the SH‐SY5Y cells, to …
present study, we used a most widely used cell line in study of PD, the SH‐SY5Y cells, to …
Effects of polyphenols and their metabolites on age-related diseases
Aging contributes to the progressive loss of cellular biological functions and increases the
risk of age-related diseases. Cardiovascular diseases, some neurological disorders and …
risk of age-related diseases. Cardiovascular diseases, some neurological disorders and …
[HTML][HTML] Multi-target effects of ß-caryophyllene and carnosic acid at the crossroads of mitochondrial dysfunction and neurodegeneration: from oxidative stress to …
R Iorio, G Celenza, S Petricca - Antioxidants, 2022 - mdpi.com
Inflammation and oxidative stress are interlinked and interdependent processes involved in
many chronic diseases, including neurodegeneration, diabetes, cardiovascular diseases …
many chronic diseases, including neurodegeneration, diabetes, cardiovascular diseases …
An updated review of protective effects of rosemary and its active constituents against natural and chemical toxicities
Natural and chemical toxic agents cause severe adverse effects on people's health in a
variety of exposing ways. Herbal medications have taken into consideration as alternative …
variety of exposing ways. Herbal medications have taken into consideration as alternative …
α-Cyperone inhibits LPS-induced inflammation in BV-2 cells through activation of Akt/Nrf2/HO-1 and suppression of the NF-κB pathway
B Huang, D He, G Chen, X Ran, W Guo, X Kan… - Food & function, 2018 - pubs.rsc.org
Accumulating evidence has shown that activated microglia cause inflammatory immune
response, which could lead to neurodegenerative diseases such as Parkinson's disease …
response, which could lead to neurodegenerative diseases such as Parkinson's disease …
α-Cyperone Attenuates H2O2-Induced Oxidative Stress and Apoptosis in SH-SY5Y Cells via Activation of Nrf2
B Huang, J Liu, S Fu, Y Zhang, Y Li, D He… - Frontiers in …, 2020 - frontiersin.org
α-Cyperone, extracted from Cyperus rotundus, has been reported to inhibit microglia-
mediated neuroinflammation. Oxidative stress and apoptosis play crucial roles in the course …
mediated neuroinflammation. Oxidative stress and apoptosis play crucial roles in the course …