Chalcone is a bioactive flavonoid found in various plants, such as Angelica archangelica,
Pueraria lobata, and Glycyrrhiza glabra. It has been studied extensively in the field of …

Background: Quassinoids are degraded triterpene compounds that can be obtained from
various species of the Simaroubaceae plant family, including Eurycoma longifolia …

Background Silene undulata is historically used for inducing vivid and prophetic lucid
dreams, but limited information exists on its phytochemical composition and potential …

Cancer poses a significant global health challenge due to its high mortality rate and complex
treatment strategies. Methylenetetrahydrofolate dehydrogenase 2 (MTHFD2), which is …

Alzheimer's disease, characterized by a decline in cognitive functions, is frequently
associated with decreased levels of acetylcholine due to the overactivity of …

Pyridone heterocycles, such as furo [2, 3-b] pyridines, have emerged as prominent scaffolds
in medicinal chemistry due to their versatile pharmacological properties, including significant …

The study aims to investigate various aspects of synthesized mono-chalcone compounds 5
and 8 concerning breast cancer, including network pharmacology, molecular docking …

Abstract New series of 4, 6-diheteroarylpyrimidine-2ـamines (4a-e) and (5a-c) were
prepared by cyclization of particular chalcones (2) or (3) with guanidine nitrate in the …

Breast cancer remains a significant challenge in oncology, highlighting the need for
alternative therapeutic strategies that target necroptosis to overcome resistance to …

This study aimed to explore the potential of Urtica dioica (U. dioica) ethanolic leaf extract for
cancer treatment by identifying its components, evaluating its effects on cancer cell lines …