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Atherosclerosis: Known and unknown
J Fan, T Watanabe - Pathology international, 2022 - Wiley Online Library
Atherosclerotic disease, such as myocardial infarction and stroke, is the number one killer
worldwide. Atherosclerosis is considered to be caused by multiple factors, including genetic …
worldwide. Atherosclerosis is considered to be caused by multiple factors, including genetic …
Metabolism of tissue macrophages in homeostasis and pathology
Cellular metabolism orchestrates the intricate use of tissue fuels for catabolism and
anabolism to generate cellular energy and structural components. The emerging field of …
anabolism to generate cellular energy and structural components. The emerging field of …
Atherosclerosis and inflammation: Insights from the theory of general pathological processes
E Gusev, A Sarapultsev - International Journal of Molecular Sciences, 2023 - mdpi.com
Recent advances have greatly improved our understanding of the molecular mechanisms
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …
The metabolic signature of macrophage responses
Macrophages are a heterogeneous population of immune cells playing several and diverse
functions in homeostatic and immune responses. The broad spectrum of macrophage …
functions in homeostatic and immune responses. The broad spectrum of macrophage …
Treatment of atherosclerosis by macrophage-biomimetic nanoparticles via targeted pharmacotherapy and sequestration of proinflammatory cytokines
Vascular disease remains the leading cause of death and disability, the etiology of which
often involves atherosclerosis. The current treatment of atherosclerosis by pharmacotherapy …
often involves atherosclerosis. The current treatment of atherosclerosis by pharmacotherapy …
Inflammation and its resolution in atherosclerosis: mediators and therapeutic opportunities
Atherosclerosis is a lipid-driven inflammatory disease of the arterial intima in which the
balance of pro-inflammatory and inflammation-resolving mechanisms dictates the final …
balance of pro-inflammatory and inflammation-resolving mechanisms dictates the final …
Microanatomy of the human atherosclerotic plaque by single-cell transcriptomics
Rationale: Atherosclerotic lesions are known for their cellular heterogeneity, yet the
molecular complexity within the cells of human plaques has not been fully assessed …
molecular complexity within the cells of human plaques has not been fully assessed …
Macrophage-Targeted Sonodynamic/Photothermal Synergistic Therapy for Preventing Atherosclerotic Plaque Progression Using CuS/TiO2 Heterostructured …
Sonodynamic therapy (SDT) and photothermal therapy (PTT) are two effective strategies for
the treatment of atherosclerotic plaques. However, the low yield of reactive oxygen species …
the treatment of atherosclerotic plaques. However, the low yield of reactive oxygen species …
The immune cell landscape in kidneys of patients with lupus nephritis
Lupus nephritis is a potentially fatal autoimmune disease for which the current treatment is
ineffective and often toxic. To develop mechanistic hypotheses of disease, we analyzed …
ineffective and often toxic. To develop mechanistic hypotheses of disease, we analyzed …
Macrophage plasticity, polarization, and function in health and disease
A Shapouri‐Moghaddam… - Journal of cellular …, 2018 - Wiley Online Library
Macrophages are heterogeneous and their phenotype and functions are regulated by the
surrounding micro‐environment. Macrophages commonly exist in two distinct subsets: 1) …
surrounding micro‐environment. Macrophages commonly exist in two distinct subsets: 1) …