Perivascular spaces and brain waste clearance systems: relevance for neurodegenerative and cerebrovascular pathology

K Gouveia-Freitas, AJ Bastos-Leite - Neuroradiology, 2021 - Springer
Perivascular spaces (PVS) of the brain, often called Virchow-Robin spaces, comprise fluid,
cells and connective tissue, and are externally limited by astrocytic endfeet. PVS are …

[HTML][HTML] Imaging perivascular space structure and function using brain MRI

G Barisano, KM Lynch, F Sibilia, H Lan, NC Shih… - Neuroimage, 2022 - Elsevier
In this article, we provide an overview of current neuroimaging methods for studying
perivascular spaces (PVS) in humans using brain MRI. In recent years, an increasing …

Perivascular space dilation is associated with vascular amyloid-β accumulation in the overlying cortex

V Perosa, J Oltmer, LP Munting, WM Freeze… - Acta …, 2022 - Springer
Perivascular spaces (PVS) are compartments surrounding cerebral blood vessels that
become visible on MRI when enlarged. Enlarged PVS (EPVS) are commonly seen in …

The effect of prolonged spaceflight on cerebrospinal fluid and perivascular spaces of astronauts and cosmonauts

G Barisano, F Sepehrband… - Proceedings of the …, 2022 - National Acad Sciences
Long-duration spaceflight induces changes to the brain and cerebrospinal fluid
compartments and visual acuity problems known as spaceflight-associated neuro-ocular …

Assessment of the DTI‐ALPS parameter along the perivascular space in older adults at risk of dementia

CE Steward, VK Venkatraman, E Lui… - Journal of …, 2021 - Wiley Online Library
ABSTRACT BACKGROUND AND PURPOSE Recently, there has been growing interest in
the glymphatic system (the functional waste clearance pathway for the central nervous …

Association of MRI indices of glymphatic system with amyloid deposition and cognition in mild cognitive impairment and Alzheimer disease

K Kamagata, C Andica, K Takabayashi, Y Saito… - Neurology, 2022 - AAN Enterprises
Background and Objectives The glymphatic system is a whole-brain perivascular network,
which promotes CSF/interstitial fluid exchange. Alterations to this system may play a pivotal …

Glymphatic clearance estimated using diffusion tensor imaging along perivascular spaces is reduced after traumatic brain injury and correlates with plasma …

T Butler, L Zhou, I Ozsahin, XH Wang… - Brain …, 2023 - academic.oup.com
The glymphatic system is a perivascular fluid clearance system, most active during sleep,
considered important for clearing the brain of waste products and toxins. Glymphatic failure …

Global and regional changes in perivascular space in idiopathic and familial Parkinson's disease

EK Donahue, A Murdos, MW Jakowec… - Movement …, 2021 - Wiley Online Library
Background The glymphatic system, including the perivascular space (PVS), plays a critical
role in brain homeostasis. Although mounting evidence from Alzheimer's disease has …

Perivascular spaces, glymphatic system and MR

L Yu, X Hu, H Li, Y Zhao - Frontiers in Neurology, 2022 - frontiersin.org
The importance of the perivascular space (PVS) as one of the imaging markers of cerebral
small vessel disease (CSVD) has been widely appreciated by the neuroradiologists. The …

Noninvasive magnetic resonance imaging measures of glymphatic system activity

K Kamagata, Y Saito, C Andica… - Journal of Magnetic …, 2024 - Wiley Online Library
The comprehension of the glymphatic system, a postulated mechanism responsible for the
removal of interstitial solutes within the central nervous system (CNS), has witnessed …