Plasmodium Genomics and Genetics: New Insights into Malaria Pathogenesis, Drug Resistance, Epidemiology, and Evolution

X Su, KD Lane, L **a, JM Sá… - Clinical microbiology …, 2019 - journals.asm.org
Protozoan Plasmodium parasites are the causative agents of malaria, a deadly disease that
continues to afflict hundreds of millions of people every year. Infections with malaria …

Chloroquine Resistance in Plasmodium vivax

JK Baird - Antimicrobial agents and chemotherapy, 2004 - journals.asm.org
Emerging resistance to chloroquine (CQ) by Plasmodium vivax threatens the health of the
hundreds of millions of people routinely exposed to the risk of infection with this organism …

Comparative genomics of the neglected human malaria parasite Plasmodium vivax

JM Carlton, JH Adams, JC Silva, SL Bidwell, H Lorenzi… - Nature, 2008 - nature.com
The human malaria parasite Plasmodium vivax is responsible for 25–40% of the∼ 515
million annual cases of malaria worldwide. Although seldom fatal, the parasite elicits severe …

The malaria parasite Plasmodium vivax exhibits greater genetic diversity than Plasmodium falciparum

DE Neafsey, K Galinsky, RHY Jiang, L Young… - Nature …, 2012 - nature.com
We sequenced and annotated the genomes of four P. vivax strains collected from disparate
geographic locations, tripling the number of genome sequences available for this …

A monkey's tale: The origin of Plasmodium vivax as a human malaria parasite

AA Escalante, OE Cornejo, DE Freeland… - Proceedings of the …, 2005 - pnas.org
The high prevalence of Duffy negativity (lack of the Duffy blood group antigen) among
human populations in sub-Saharan Africa has been used to argue that Plasmodium vivax …

Host Switch Leads to Emergence of Plasmodium vivax Malaria in Humans

J Mu, DA Joy, J Duan, Y Huang… - Molecular biology …, 2005 - academic.oup.com
The geographical origin of Plasmodium vivax, the most widespread human malaria parasite,
is controversial. Although genetic closeness to Asian primate malarias has been confirmed …

Clinical features of children hospitalized with malaria—a study from Bikaner, northwest India

DK Kochar, GS Tanwar, PC Khatri… - … American journal of …, 2010 - pmc.ncbi.nlm.nih.gov
Severe Plasmodium vivax malaria in adults has been reported from Bikaner (northwestern
India) but the reports on children are scanty. This prospective study was done on 303 …

Contrasting genetic structure in Plasmodium vivax populations from Asia and South America

M Imwong, S Nair, S Pukrittayakamee… - International journal for …, 2007 - Elsevier
Populations of Plasmodium falciparum show striking differences in linkage disequilibrium,
population differentiation and diversity, but only fragmentary data exists on the genetic …

Molecular epidemiology of malaria

DJ Conway - Clinical Microbiology Reviews, 2007 - journals.asm.org
Malaria persists as an undiminished global problem, but the resources available to address
it have increased. Many tools for understanding its biology and epidemiology are well …

Plasmodium vivax Biology: Insights Provided by Genomics, Transcriptomics and Proteomics

C Bourgard, L Albrecht, ACAV Kayano… - Frontiers in cellular …, 2018 - frontiersin.org
During the last decade, the vast omics field has revolutionized biological research,
especially the genomics, transcriptomics and proteomics branches, as technological tools …