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[HTML][HTML] Recent development of computational cluster analysis methods for single-molecule localization microscopy images
With the development of super-resolution imaging techniques, it is crucial to understand
protein structure at the nanoscale in terms of clustering and organization in a cell. However …
protein structure at the nanoscale in terms of clustering and organization in a cell. However …
Single-molecule localization microscopy reveals STING clustering at the trans-Golgi network through palmitoylation-dependent accumulation of cholesterol
H Kemmoku, K Takahashi, K Mukai, T Mori… - Nature …, 2024 - nature.com
Stimulator of interferon genes (STING) is critical for the type I interferon response to
pathogen-or self-derived DNA in the cytosol. STING may function as a scaffold to activate …
pathogen-or self-derived DNA in the cytosol. STING may function as a scaffold to activate …
Quantitative Single‐Molecule Electrochemiluminescence Bioassay
W Zhu, J Dong, G Ruan, Y Zhou… - Angewandte Chemie …, 2023 - Wiley Online Library
A single‐molecule electrochemiluminescence bioassay is developed here which allows
imaging and direct quantification of single biomolecules. Imaging single biomolecules is …
imaging and direct quantification of single biomolecules. Imaging single biomolecules is …
A framework for evaluating the performance of SMLM cluster analysis algorithms
Single-molecule localization microscopy (SMLM) generates data in the form of coordinates
of localized fluorophores. Cluster analysis is an attractive route for extracting biologically …
of localized fluorophores. Cluster analysis is an attractive route for extracting biologically …
Recent advances in fluorescent nanoparticles for stimulated emission depletion imaging
L Qi, S Liu, J **, X Yao, L Chen, D Yang, Y Liu… - Biosensors, 2024 - mdpi.com
Stimulated emission depletion (STED) microscopy, as a popular super-resolution imaging
technique, has been widely used in bio-structure analysis and resolving the dynamics of …
technique, has been widely used in bio-structure analysis and resolving the dynamics of …
Quantitatively lighting up the spatial organization of CD47/SIRPα immune checkpoints on the cellular membrane with single-molecule localization microscopy
Y Wei, M Zhao, T He, N Chen, L Rao, L Chen… - ACS …, 2023 - ACS Publications
Immunotherapy including immune checkpoint inhibition has reinvigorated the current cancer
treatment field. The development of efficient cancer immunotherapies depends on a …
treatment field. The development of efficient cancer immunotherapies depends on a …
High-precision estimation of emitter positions using Bayesian grou** of localizations
Single-molecule localization microscopy super-resolution methods rely on stochastic
blinking/binding events, which often occur multiple times from each emitter over the course …
blinking/binding events, which often occur multiple times from each emitter over the course …
Quantitative Analysis of Protein–Protein Equilibrium Constants in Cellular Environments Using Single-Molecule Localization Microscopy
LF Marcano-García, C Zaza, OPL Dalby… - Nano Letters, 2024 - ACS Publications
Current methods for determining equilibrium constants often operate in three-dimensional
environments, which may not accurately reflect interactions with membrane-bound proteins …
environments, which may not accurately reflect interactions with membrane-bound proteins …
Nonblinking core–multishell InP/ZnSe/ZnS quantum dot bioconjugates for super-resolution imaging
L Zhou, B Yu, L Huang, H Cao, D Lin… - ACS Applied Nano …, 2022 - ACS Publications
Colloidal quantum dots (QDs) are vital fluorescent probes with several optical features
superior to those found in organic dyes for microscopy imaging. However, the emission …
superior to those found in organic dyes for microscopy imaging. However, the emission …
Exploring fetal brain tumor glioblastoma symptom verification with self organizing maps and vulnerability data analysis
SK Natarajan, JS, SK Mathivanan, H Rajadurai… - Scientific Reports, 2024 - nature.com
Brain tumor glioblastoma is a disease that is caused for a child who has abnormal cells in
the brain, which is found using MRI “Magnetic Resonance Imaging” brain image using a …
the brain, which is found using MRI “Magnetic Resonance Imaging” brain image using a …