Increases in calorie consumption and sedentary lifestyles are fuelling a global pandemic of
cardiometabolic diseases, including coronary artery disease, diabetes mellitus …

Sphingolipids are a specialized group of lipids essential to the composition of the plasma
membrane of many cell types; however, they are primarily localized within the nervous …

Background Anti-cancer therapy is often a cause of premature ovarian insufficiency and
infertility since the ovarian follicle reserve is extremely sensitive to the effects of …

Despite major progress in interventional and medical treatments, myocardial infarction (MI)
and subsequent development of heart failure (HF) are still associated with high mortality …

Sphingolipids, including the two central bioactive lipids ceramide and sphingosine-1-
phosphate (S1P), have opposing roles in regulating cancer cell death and survival …

Pancreatic and lung cancers frequently develop resistance to chemotherapy-induced cell
apoptosis during the treatment, indicating that targeting nonapoptotic-related pathways …

Lipids are abundant and play essential roles in human health and disease. The main
functions of lipids are building blocks for membrane biogenesis. However, lipids are also …

Lipid metabolism plays a major role in the regulation of the immune system. Exogenous
(dietary and microbial-derived) and endogenous (non-microbial-derived) lipids play a direct …

Green tea is a beverage that is widely consumed worldwide and is believed to exert effects
on different diseases, including cancer. The major components of green tea are catechins, a …

Utilization of lipids as energy substrates after birth causes cardiomyocyte (CM) cell-cycle
arrest and loss of regenerative capacity in mammalian hearts. Beyond energy provision …