Volumetric muscle loss (VML) injuries present a complex and heterogeneous clinical
problem that results in a chronic loss of muscle tissue and strength. The primary limitation to …

The rehabilitation of individuals with lower extremity injury is a common but complex
problem for the surgical and rehabilitative teams. Basic science tenets of fracture and soft …

Biofabrication can be a tool to three-dimensionally (3D) print muscle cells embedded inside
hydrogel biomaterials, ultimately aiming to mimic the complexity of the native muscle tissue …

Current therapeutic approaches for volumetric muscle loss (VML) face challenges due to
limited graft availability and insufficient bioactivities. To overcome these limitations, tissue …

Mesoporous bioactive glasses (MBGs) exhibit a high surface area and a highly ordered
mesoporous structure. MBGs have potential for both hard and soft tissue engineering …

The frank loss of a large volume of skeletal muscle (ie, volumetric muscle loss [VML]) can
lead to functional debilitation and presents a significant problem to civilian and military …

Soft tissue injuries involving volumetric muscle loss (VML) are defined as the traumatic or
surgical loss of skeletal muscle with resultant functional impairment and represent a …

Background: High-energy extremity trauma is common in combat. Orthotic options for
patients whose lower extremities have been salvaged are limited. A custom energy-storing …

Background Given the clinical practice of prescribing physical rehabilitation for the treatment
of VML injuries, the present study examined the functional and histomorphological …

Blood flow restriction (BFR) training is a technique shown to be safe and effective at
increasing muscular strength and endurance in healthy fitness populations and is under …