Intermittent metabolic switching and vascular cognitive impairment
Intermittent fasting (IF), a dietary pattern alternating between eating and fasting periods
within a 24-hour cycle, has garnered recognition for its potential to enhance both healthspan …
within a 24-hour cycle, has garnered recognition for its potential to enhance both healthspan …
When the central integrator disintegrates: A review of the role of the thalamus in cognition and dementia
The thalamus is a complex neural structure with numerous anatomical subdivisions and
intricate connectivity patterns. In recent decades, the traditional view of the thalamus as a …
intricate connectivity patterns. In recent decades, the traditional view of the thalamus as a …
[HTML][HTML] White matter hyperintensity volume and poststroke cognition: an individual patient data pooled analysis of 9 ischemic stroke cohort studies
BACKGROUND: White matter hyperintensities (WMH) are associated with cognitive
dysfunction after ischemic stroke. Yet, uncertainty remains about affected domains, the role …
dysfunction after ischemic stroke. Yet, uncertainty remains about affected domains, the role …
Regional cortical thinning, demyelination and iron loss in cerebral small vessel disease
The link between white matter hyperintensities (WMH) and cortical thinning is thought to be
an important pathway by which WMH contributes to cognitive deficits in cerebral small …
an important pathway by which WMH contributes to cognitive deficits in cerebral small …
Can white matter hyperintensities based Fazekas visual assessment scales inform about Alzheimer's disease pathology in the population?
Background White matter hyperintensities (WMH) are considered hallmark features of
cerebral small vessel disease and have recently been linked to Alzheimer's disease (AD) …
cerebral small vessel disease and have recently been linked to Alzheimer's disease (AD) …
[HTML][HTML] Cerebral white matter hyperintensity volumes: normative age-and sex-specific values from 15 population-based cohorts comprising 14,876 individuals
White matter hyperintensities (WMH) increase with age, with marked interindividual
variation. There is a need for normative data by age and sex, to improve individualized WMH …
variation. There is a need for normative data by age and sex, to improve individualized WMH …
Enhancing cognitive performance prediction by white matter hyperintensity connectivity assessment
White matter hyperintensities of presumed vascular origin (WMH) are associated with
cognitive impairment and are a key imaging marker in evaluating brain health. However …
cognitive impairment and are a key imaging marker in evaluating brain health. However …
Advances in Stroke: Brain Health in 2023
The best solution continues to be prevention and preservation of brain health. Brain health is
defined as “optimal capacity to function adaptively in the environment” by the American …
defined as “optimal capacity to function adaptively in the environment” by the American …
[HTML][HTML] Structural damage-driven brain compensation among near-centenarians and centenarians without dementia
Compensation has been proposed as a mechanism to explain how individuals in very old
age remain able to maintain normal cognitive functioning. Previous studies have provided …
age remain able to maintain normal cognitive functioning. Previous studies have provided …
White matter hyperintensity patterns: associations with comorbidities, amyloid, and cognition
Abstract Background White matter hyperintensities (WMHs) are often measured globally, but
spatial patterns of WMHs could underlie different risk factors and neuropathological and …
spatial patterns of WMHs could underlie different risk factors and neuropathological and …