Fluid mechanics of heart valves and their replacements

F Sotiropoulos, TB Le, A Gilmanov - Annual Review of Fluid …, 2016 - annualreviews.org
As the pulsatile cardiac blood flow drives the heart valve leaflets to open and close, the flow
in the vicinity of the valve resembles a pulsed jet through a nonaxisymmetric orifice with a …

Toward patient-specific simulations of cardiac valves: state-of-the-art and future directions

E Votta, TB Le, M Stevanella, L Fusini, EG Caiani… - Journal of …, 2013 - Elsevier
Recent computational methods enabling patient-specific simulations of native and prosthetic
heart valves are reviewed. Emphasis is placed on two critical components of such …

An image-based computational fluid dynamics study of mitral regurgitation in presence of prolapse

L Bennati, C Vergara, V Giambruno, I Fumagalli… - Cardiovascular …, 2023 - Springer
Purpose In this work we performed an imaged-based computational study of the systolic
fluid dynamics in presence of mitral valve regurgitation (MVR). In particular, we compared …

Turbulent blood dynamics in the left heart in the presence of mitral regurgitation: a computational study based on multi-series cine-MRI

L Bennati, V Giambruno, F Renzi, V Di Nicola… - … and Modeling in …, 2023 - Springer
In this work, we performed a computational image-based study of blood dynamics in the
whole left heart, both in a healthy subject and in a patient with mitral valve regurgitation. We …

[HTML][HTML] Effect of the mitral valve on diastolic flow patterns

JH Seo, V Vedula, T Abraham, AC Lardo, F Dawoud… - Physics of …, 2014 - pubs.aip.org
The leaflets of the mitral valve interact with the mitral jet and significantly impact diastolic
flow patterns, but the effect of mitral valve morphology and kinematics on diastolic flow and …

Geometric description for the anatomy of the mitral valve: a review

D Oliveira, J Srinivasan, D Espino, K Buchan… - Journal of …, 2020 - Wiley Online Library
The mitral valve is a complex anatomical structure whose physiological functioning relies on
the biomechanical properties and structural integrity of its components. Their compromise …

Finite element modeling of mitral valve dynamic deformation using patient-specific multi-slices computed tomography scans

Q Wang, W Sun - Annals of biomedical engineering, 2013 - Springer
The objective of this study was to develop a patient-specific finite element (FE) model of a
human mitral valve. The geometry of the mitral valve was reconstructed from multi-slice …

An investigation of the anisotropic mechanical properties and anatomical structure of porcine atrioventricular heart valves

S Jett, D Laurence, R Kunkel, AR Babu… - Journal of the …, 2018 - Elsevier
Valvular heart diseases are complex disorders, varying in pathophysiological mechanism
and affected valve components. Understanding the effects of these diseases on valve …

Heart valve biomechanics and underlying mechanobiology

S Ayoub, G Ferrari, RC Gorman… - Comprehensive …, 2016 - pmc.ncbi.nlm.nih.gov
Heart valves control unidirectional blood flow within the heart during the cardiac cycle. They
have a remarkable ability to withstand the demanding mechanical environment of the heart …

A coupled mitral valve—left ventricle model with fluid–structure interaction

H Gao, L Feng, N Qi, C Berry, BE Griffith… - Medical engineering & …, 2017 - Elsevier
Understanding the interaction between the valves and walls of the heart is important in
assessing and subsequently treating heart dysfunction. This study presents an integrated …