This review summarizes recent evidence that prenatal exposure to diverse environmental
chemicals dysregulates the fetal epigenome, with potential consequences for subsequent …

There is general agreement that vitamin D deficiency is a worldwide health problem. This is
due in part to the lack of appreciation that sunlight is an important source of vitamin D. There …

Epigenetic marks in an organism can be altered by environmental factors throughout life.
Although changes in the epigenetic code can be positive, some are associated with severe …

Psychiatric diseases are multifaceted disorders with complex etiology, recognized to have
strong heritable components. Despite intense research efforts, genetic loci that substantially …

Traumatic stress in early-life increases the risk for cognitive and neuropsychiatric disorders
later in life. Such early stress can also impact the progeny even if not directly exposed, likely …

Imprinted loci play a critical role in fetal development. Their expression is often regulated by
CCCTC-binding factor (CTCF) protein binding at imprinting control regions (ICRs). Prenatal …

Background Human and animal studies indicate that vulnerability to stress may be heritable
and that changes in germline may mediate some transgenerational effects. Corticotropin …

John Bowlby (1969/1982) was the first to give the psychological concept of human
attachment a strong base in evolutionary theory. He was convinced that early attachment …

Play behavior in juvenile primates, rats and other species is sexually dimorphic, with males
showing more play than females. In mice, sex differences in juvenile play have only been …

Background Although in all sexually reproducing organisms an individual has a mother and
a father, non-genetic inheritance has been predominantly studied in mothers. Paternal …