Diabetes mellitus is a group of metabolic disorders characterized by hyperglycemia caused
by resistance to insulin action, inadequate insulin secretion, or excessive glucagon …

Zika virus (ZIKV) is an arbovirus whose infection in humans can lead to severe outcomes.
This article reviews studies reporting the anti-ZIKV activity of natural products (NPs) and …

Berberine is a quaternary ammonium isoquinoline alkaloid derived from traditional Chinese
medicines Coptis chinensis and Phellodendron chinense. It has many pharmacological …

Berberine is a natural alkaloid with a broad spectrum of biological activity. Derivatives of
berberine with reduced structural stability are particularly promising for pharmacological …

Berberine is a well-known phytochemical with significant antiviral activity against a wide
range of viruses. Due to having a unique backbone consisting of four interconnected rings, it …

The Zika virus (ZIKV) is believed to cause birth defects, and no anti-ZIKV drugs have been
approved by medical organizations to date. Starting from antimicrobial lead compounds with …

Abstract Scopes and Objectives: We analyzed some aspects of the first historical outbreak of
Zika that occurred in Salta, Argentina, in the year 2017. We obtained elementary estimates …

This study outlines a detailed methodology for synthesizing isoxazole derivatives intended
for medicinal and materials applications. The approach involves employing condensation …

Introduction: With a tremendous spike in the cases of anxiety in recent years, scientists are
looking for herbal drug alternatives for its treatment as all the conventional medication …

Chalcone scaffolds play an important role in anticancer drug design. In this article, the
chalcone derivatives containing heterocyclic moiety (quinazolinone, benzimidazole …