Mechanisms of mitochondrial respiratory adaptation
Mitochondrial energetic adaptations encompass a plethora of conserved processes that
maintain cell and organismal fitness and survival in the changing environment by adjusting …
maintain cell and organismal fitness and survival in the changing environment by adjusting …
Mitochondrial proteins: from biogenesis to functional networks
Mitochondria are essential for the viability of eukaryotic cells as they perform crucial
functions in bioenergetics, metabolism and signalling and have been associated with …
functions in bioenergetics, metabolism and signalling and have been associated with …
[HTML][HTML] Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context
Mitochondria are key organelles for cellular energetics, metabolism, signaling, and quality
control and have been linked to various diseases. Different views exist on the composition of …
control and have been linked to various diseases. Different views exist on the composition of …
Mechanisms and regulation of protein synthesis in mitochondria
E Kummer, N Ban - Nature Reviews Molecular Cell Biology, 2021 - nature.com
Mitochondria are cellular organelles responsible for generation of chemical energy in the
process called oxidative phosphorylation. They originate from a bacterial ancestor and …
process called oxidative phosphorylation. They originate from a bacterial ancestor and …
Mitochondrial machineries for protein import and assembly
Mitochondria are essential organelles with numerous functions in cellular metabolism and
homeostasis. Most of the> 1,000 different mitochondrial proteins are synthesized as …
homeostasis. Most of the> 1,000 different mitochondrial proteins are synthesized as …
Mitochondrial protein transport: Versatility of translocases and mechanisms
Biogenesis of mitochondria requires the import of approximately 1,000 different precursor
proteins into and across the mitochondrial membranes. Mitochondria exhibit a wide variety …
proteins into and across the mitochondrial membranes. Mitochondria exhibit a wide variety …
Mitochondrial disorders of the OXPHOS system
E Fernandez‐Vizarra, M Zeviani - FEBS letters, 2021 - Wiley Online Library
Mitochondrial disorders are among the most frequent inborn errors of metabolism, their
primary cause being the dysfunction of the oxidative phosphorylation system (OXPHOS) …
primary cause being the dysfunction of the oxidative phosphorylation system (OXPHOS) …
The assembly pathway of mitochondrial respiratory chain complex I
S Guerrero-Castillo, F Baertling, D Kownatzki… - Cell metabolism, 2017 - cell.com
Mitochondrial complex I is the largest integral membrane enzyme of the respiratory chain
and consists of 44 different subunits encoded in the mitochondrial and nuclear genome. Its …
and consists of 44 different subunits encoded in the mitochondrial and nuclear genome. Its …
Mitochondrial structure and bioenergetics in normal and disease conditions
M Protasoni, M Zeviani - International journal of molecular sciences, 2021 - mdpi.com
Mitochondria are ubiquitous intracellular organelles found in almost all eukaryotes and
involved in various aspects of cellular life, with a primary role in energy production. The …
involved in various aspects of cellular life, with a primary role in energy production. The …
Assembly of mammalian oxidative phosphorylation complexes I–V and supercomplexes
A Signes, E Fernandez-Vizarra - Essays in biochemistry, 2018 - portlandpress.com
The assembly of the five oxidative phosphorylation system (OXPHOS) complexes in the
inner mitochondrial membrane is an intricate process. The human enzymes comprise core …
inner mitochondrial membrane is an intricate process. The human enzymes comprise core …