Matrix-assisted laser desorption ionization–time of flight mass spectrometry: a fundamental shift in the routine practice of clinical microbiology

AE Clark, EJ Kaleta, A Arora… - Clinical microbiology …, 2013 - Am Soc Microbiol
Within the past decade, clinical microbiology laboratories experienced revolutionary
changes in the way in which microorganisms are identified, moving away from slow …

Applications of MALDI-TOF mass spectrometry in clinical diagnostic microbiology

A Croxatto, G Prod'hom, G Greub - FEMS microbiology reviews, 2012 - academic.oup.com
Until recently, microbial identification in clinical diagnostic laboratories has mainly relied on
conventional phenotypic and gene sequencing identification techniques. The development …

High-throughput identification of bacteria and yeast by matrix-assisted laser desorption ionization-time of flight mass spectrometry in conventional medical …

SQ Van Veen, ECJ Claas… - Journal of clinical …, 2010 - Am Soc Microbiol
Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS)
is suitable for high-throughput and rapid diagnostics at low costs and can be considered an …

[HTML][HTML] Blood culture-based diagnosis of bacteraemia: state of the art

O Opota, A Croxatto, G Prod'Hom, G Greub - Clinical Microbiology and …, 2015 - Elsevier
Blood culture remains the best approach to identify the incriminating microorganisms when
a bloodstream infection is suspected, and to guarantee that the antimicrobial treatment is …

Mass spectrometry tools for the classification and identification of bacteria

S Sauer, M Kliem - Nature reviews microbiology, 2010 - nature.com
Mass spectrometry has become an important analytical tool in biology in the past two
decades. In principle, mass spectrometry offers high-throughput, sensitive and specific …

MALDI TOF MS profiling of bacteria at the strain level: a review

TR Sandrin, JE Goldstein… - Mass spectrometry …, 2013 - Wiley Online Library
Since the advent of the use of matrix‐assisted laser desorption/ionization (MALDI) time‐of‐
flight mass spectrometry (TOF MS) as a tool for microbial characterization, efforts to increase …

[BOOK][B] MALDI MS: a practical guide to instrumentation, methods and applications

F Hillenkamp, J Peter-Katalinic - 2013 - books.google.com
This authoritative book on MALDI MS, now finally available in its second edition and edited
by one of its inventors, gives an in-depth description of the many different applications, along …

MALDI-TOF-mass spectrometry applications in clinical microbiology

P Seng, JM Rolain, PE Fournier, B La Scola… - Future …, 2010 - Taylor & Francis
MALDI-TOF-mass spectrometry (MS) has been successfully adapted for the routine
identification of microorganisms in clinical microbiology laboratories in the past 10 years …

Matrix-assisted laser desorption ionization–time of flight mass spectrometry-based functional assay for rapid detection of resistance against β-lactam antibiotics

K Sparbier, S Schubert, U Weller… - Journal of clinical …, 2012 - Am Soc Microbiol
Resistance against β-lactam antibiotics is a growing challenge for managing severe
bacterial infections. The rapid and cost-efficient determination of β-lactam resistance is an …

Applications and continued evolution of glycan imaging mass spectrometry

CT McDowell, X Lu, AS Mehta… - Mass spectrometry …, 2023 - Wiley Online Library
Glycosylation is an important posttranslational modifier of proteins and lipid conjugates
critical for the stability and function of these macromolecules. Particularly important are N …