Electrical synapses and their functional interactions with chemical synapses

AE Pereda - Nature Reviews Neuroscience, 2014 - nature.com
Brain function relies on the ability of neurons to communicate with each other. Interneuronal
communication primarily takes place at synapses, where information from one neuron is …

Synaptic functions of endocannabinoid signaling in health and disease

A Araque, PE Castillo, OJ Manzoni, R Tonini - Neuropharmacology, 2017 - Elsevier
Endocannabinoids (eCBs) are a family of lipid molecules that act as key regulators of
synaptic transmission and plasticity. They are synthetized “on demand” following …

Endocannabinoids potentiate synaptic transmission through stimulation of astrocytes

M Navarrete, A Araque - Neuron, 2010 - cell.com
Endocannabinoids and their receptor CB1 play key roles in brain function. Astrocytes
express CB1Rs that are activated by endocannabinoids released by neurons. However, the …

Mixed-dimensional nanoparticle–nanowire channels for flexible optoelectronic artificial synapse with enhanced photoelectric response and asymmetric bidirectional …

H Wei, Z Xu, Y Ni, L Yang, L Sun, J Gong, S Zhang… - Nano Letters, 2023 - ACS Publications
A mixed-dimensional dual-channel synaptic transistor composed of inorganic nanoparticles
and organic nanowires was fabricated to expand the photoelectric gain range. The device …

Endocannabinoid signaling and long-term synaptic plasticity

BD Heifets, PE Castillo - Annual review of physiology, 2009 - annualreviews.org
Endocannabinoids (eCBs) are key activity-dependent signals regulating synaptic
transmission throughout the central nervous system. Accordingly, eCBs are involved in …

Activity-dependent regulation of synapses by retrograde messengers

WG Regehr, MR Carey, AR Best - Neuron, 2009 - cell.com
Throughout the brain, postsynaptic neurons release substances from their cell bodies and
dendrites that regulate the strength of the synapses they receive. Diverse chemical …

Acute effects of different types of cannabis on young adult and adolescent resting-state brain networks

N Ertl, TP Freeman, C Mokrysz, S Ofori… - …, 2024 - nature.com
Adolescence is a time of rapid neurodevelopment and the endocannabinoid system is
particularly prone to change during this time. Cannabis is a commonly used drug with a …

Re-membering the body: applications of computational neuroscience to the top-down control of regeneration of limbs and other complex organs

G Pezzulo, M Levin - Integrative Biology, 2015 - academic.oup.com
A major goal of regenerative medicine and bioengineering is the regeneration of complex
organs, such as limbs, and the capability to create artificial constructs (so-called biobots) …

[HTML][HTML] Gap junction-mediated electrical transmission: regulatory mechanisms and plasticity

AE Pereda, S Curti, G Hoge, R Cachope… - … et Biophysica Acta (BBA …, 2013 - Elsevier
The term synapse applies to cellular specializations that articulate the processing of
information within neural circuits by providing a mechanism for the transfer of information …

[HTML][HTML] Electrical synapses in mammalian CNS: Past eras, present focus and future directions

JI Nagy, AE Pereda, JE Rash - Biochimica et Biophysica Acta (BBA) …, 2018 - Elsevier
Gap junctions provide the basis for electrical synapses between neurons. Early studies in
well-defined circuits in lower vertebrates laid the foundation for understanding various …