Advanced PLGA hybrid scaffold with a bioactive PDRN/BMP2 nanocomplex for angiogenesis and bone regeneration using human fetal MSCs

DS Kim, JK Lee, JH Kim, J Lee, DS Kim, S An… - Science …, 2021 - science.org
Biodegradable polymers have been used with various systems for tissue engineering.
Among them, poly (lactic-co-glycolic) acid (PLGA) has been widely used as a biomaterial for …

Factors controlling degradation of biologically relevant synthetic polymers in solution and solid state

J Brito, AK Andrianov, SA Sukhishvili - ACS Applied Bio Materials, 2022 - ACS Publications
The field of biodegradable synthetic polymers, which is central for regenerative engineering
and drug delivery applications, encompasses a multitude of hydrolytically sensitive …

Porous biomaterial scaffolds for skeletal muscle tissue engineering

NG Kozan, M Joshi, ST Sicherer… - … in Bioengineering and …, 2023 - frontiersin.org
Volumetric muscle loss is a traumatic injury which overwhelms the innate repair
mechanisms of skeletal muscle and results in significant loss of muscle functionality. Tissue …

Nitric oxide‐releasing bioinspired scaffold for exquisite regeneration of osteoporotic bone via regulation of homeostasis

JK Lee, DS Kim, SY Park, SW Baek, JW Jung… - Advanced …, 2023 - Wiley Online Library
Osteoporotic bone regeneration is a challenging process which involves the occurrence of
sophisticated interactions. Although various polymeric scaffolds have been proposed for …

Porous nerve guidance conduits reinforced with braided composite structures of silk/magnesium filaments for peripheral nerve repair

S Zhang, J Wang, Z Zheng, J Yan, L Zhang, Y Li… - Acta Biomaterialia, 2021 - Elsevier
Peripheral nerve repair is a common but challenging surgical treatment. Many artificial nerve
grafts have been developed, including nerve guidance conduits (NGCs) with …

Reduced restenosis and enhanced re-endothelialization of functional biodegradable vascular scaffolds by everolimus and magnesium hydroxide

SW Baek, DS Kim, DH Song, HB Kim, S Lee… - Biomaterials …, 2022 - spj.science.org
Background Coronary artery disease is a cardiovascular disease with a high mortality and
mortality rate in modern society. Vascular stent insertion to restore blood flow is essential to …

[HTML][HTML] Continuous NO dual-generation by ZnO nanoparticle conjugated with α-lipoic acid for functional biodegradable vascular stent

SW Baek, DS Kim, JK Lee, JH Kim, S Lee… - Chemical Engineering …, 2023 - Elsevier
Coronary artery diseases are treated with a biodegradable vascular scaffold (BVS)
intervention. However, BVS need to be enhanced to avoid post-insertion side effects, which …

Promotion of bone regeneration using bioinspired PLGA/MH/ECM scaffold combined with bioactive PDRN

DS Kim, JK Lee, JW Jung, SW Baek, JH Kim, Y Heo… - Materials, 2021 - mdpi.com
Current approaches of biomaterials for the repair of critical-sized bone defects still require
immense effort to overcome numerous obstacles. The biodegradable polymer-based …

Incorporation of magnesium and zinc metallic particles in PLGA Bi-layered membranes with sequential ion release for guided bone regeneration

H Tang, C Qi, Y Bai, X Niu, X Gu… - ACS Biomaterials Science …, 2023 - ACS Publications
Guided bone regeneration (GBR) membranes are commonly used for periodontal tissue
regeneration. Due to the complications of existing GBR membranes, the design of bioactive …

PLLA composites combined with delivery system of bioactive agents for anti-inflammation and re-endothelialization

SW Baek, DS Kim, DH Song, S Lee, JK Lee, SY Park… - Pharmaceutics, 2022 - mdpi.com
The development of a biodegradable vascular scaffold (BVS) for the treatment of
cardiovascular diseases (CVDs) still requires some improvement. Among them, re …