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Amniotic fluid stem cell extracellular vesicles as a novel fetal therapy for pulmonary hypoplasia: a review on mechanisms and translational potential
Disruption of developmental processes affecting the fetal lung leads to pulmonary
hypoplasia. Pulmonary hypoplasia results from several conditions including congenital …
hypoplasia. Pulmonary hypoplasia results from several conditions including congenital …
Amniotic fluid stem cell extracellular vesicles promote lung development via TGF-beta modulation in a fetal rat model of oligohydramnios
F Doktor, RL Figueira, V Fortuna, G Biouss… - Journal of Controlled …, 2025 - Elsevier
Oligohydramnios (decreased amniotic fluid volume for gestational age) is a severe condition
associated with high morbidity and mortality mainly due to fetal pulmonary hypoplasia …
associated with high morbidity and mortality mainly due to fetal pulmonary hypoplasia …
The genetic etiologies of bilateral renal agenesis
GW Kirschen, K Blakemore, HB Al‐Kouatly… - Prenatal …, 2024 - Wiley Online Library
Objective The goal of this study was to review and analyze the medical literature for cases of
prenatal and/or postnatally diagnosed bilateral renal agenesis (BRA) and create a …
prenatal and/or postnatally diagnosed bilateral renal agenesis (BRA) and create a …
Treating adolescent opioid use disorder in primary care
SE Hadland, WH Burr, K Zoucha, CA Somberg… - JAMA …, 2024 - jamanetwork.com
Methods| We used 2021 AAP Periodic Survey data, a nationally representative random
sample of posttrainee, AAP-member pediatricians surveyed between November 2021 and …
sample of posttrainee, AAP-member pediatricians surveyed between November 2021 and …
Bilateral Renal Agenesis—Interpreting the RAFT Trial
Bilateral renal agenesis is historically considered to be universally fatal, due to pulmonary
hypoplasia resulting from failure to maintain adequate amniotic fluid from fetal urine …
hypoplasia resulting from failure to maintain adequate amniotic fluid from fetal urine …
Fetal lower urinary tract obstruction: international Delphi consensus on management and core outcome set
HJ Mustafa, A Khalil, S Johnson… - … in Obstetrics & …, 2024 - Wiley Online Library
Objectives To reach an international expert consensus on the diagnosis, prognosis and
management of fetal lower urinary tract obstruction (LUTO) by means of a Delphi procedure …
management of fetal lower urinary tract obstruction (LUTO) by means of a Delphi procedure …
Chronic Kidney Disease Takes, Palliative Care Gives: What a Pediatric Nephrologist Needs to Know About Palliative Care
M Thomas, L Mosley, TR House - Current Pediatrics Reports, 2024 - Springer
Abstract Purpose of the Review We describe palliative care (PC) and its role in pediatric
nephrology practice, debunk common misconceptions about PC, and offer examples of …
nephrology practice, debunk common misconceptions about PC, and offer examples of …
Precarious hope: Ethical considerations for offering experimental fetal therapies outside of research after initial studies in humans
S Hendriks, J Althaus, MA Atkinson… - Prenatal …, 2024 - Wiley Online Library
Objective Risks and benefits of experimental fetal therapies can remain uncertain after initial
clinical studies, especially long‐term effects. Nevertheless, pregnant individuals may …
clinical studies, especially long‐term effects. Nevertheless, pregnant individuals may …
Recent progress in xenotransplantation and its application to pediatric kidney disease
K Morimoto, S Yamanaka, T Yokoo - Pediatric Nephrology, 2025 - Springer
Patients with kidney failure require dialysis or kidney transplantation. Kidney transplantation
offers great benefits, including reduced mortality; however, many patients who wish to …
offers great benefits, including reduced mortality; however, many patients who wish to …
Fetal kidney transplantation for in utero fetuses
K Morimoto, S Yamanaka, K Matsui, Y Kinoshita… - bioRxiv, 2024 - biorxiv.org
Potter sequence, characterized by bilateral renal agenesis, oligohydramnios, and
consequent pulmonary hypoplasia, presents a significant challenge in the management of …
consequent pulmonary hypoplasia, presents a significant challenge in the management of …