Amniotic fluid stem cell extracellular vesicles as a novel fetal therapy for pulmonary hypoplasia: a review on mechanisms and translational potential

F Doktor, L Antounians, RL Figueira… - Stem Cells …, 2025 - academic.oup.com
Disruption of developmental processes affecting the fetal lung leads to pulmonary
hypoplasia. Pulmonary hypoplasia results from several conditions including congenital …

Amniotic fluid stem cell extracellular vesicles promote lung development via TGF-beta modulation in a fetal rat model of oligohydramnios

F Doktor, RL Figueira, V Fortuna, G Biouss… - Journal of Controlled …, 2025 - Elsevier
Oligohydramnios (decreased amniotic fluid volume for gestational age) is a severe condition
associated with high morbidity and mortality mainly due to fetal pulmonary hypoplasia …

The genetic etiologies of bilateral renal agenesis

GW Kirschen, K Blakemore, HB Al‐Kouatly… - Prenatal …, 2024 - Wiley Online Library
Objective The goal of this study was to review and analyze the medical literature for cases of
prenatal and/or postnatally diagnosed bilateral renal agenesis (BRA) and create a …

Treating adolescent opioid use disorder in primary care

SE Hadland, WH Burr, K Zoucha, CA Somberg… - JAMA …, 2024 - jamanetwork.com
Methods| We used 2021 AAP Periodic Survey data, a nationally representative random
sample of posttrainee, AAP-member pediatricians surveyed between November 2021 and …

Bilateral Renal Agenesis—Interpreting the RAFT Trial

C Gyamfi-Bannerman, K Marc-Aurele, K Mestan - JAMA, 2023 - jamanetwork.com
Bilateral renal agenesis is historically considered to be universally fatal, due to pulmonary
hypoplasia resulting from failure to maintain adequate amniotic fluid from fetal urine …

Fetal lower urinary tract obstruction: international Delphi consensus on management and core outcome set

HJ Mustafa, A Khalil, S Johnson… - … in Obstetrics & …, 2024 - Wiley Online Library
Objectives To reach an international expert consensus on the diagnosis, prognosis and
management of fetal lower urinary tract obstruction (LUTO) by means of a Delphi procedure …

Chronic Kidney Disease Takes, Palliative Care Gives: What a Pediatric Nephrologist Needs to Know About Palliative Care

M Thomas, L Mosley, TR House - Current Pediatrics Reports, 2024 - Springer
Abstract Purpose of the Review We describe palliative care (PC) and its role in pediatric
nephrology practice, debunk common misconceptions about PC, and offer examples of …

Precarious hope: Ethical considerations for offering experimental fetal therapies outside of research after initial studies in humans

S Hendriks, J Althaus, MA Atkinson… - Prenatal …, 2024 - Wiley Online Library
Objective Risks and benefits of experimental fetal therapies can remain uncertain after initial
clinical studies, especially long‐term effects. Nevertheless, pregnant individuals may …

Recent progress in xenotransplantation and its application to pediatric kidney disease

K Morimoto, S Yamanaka, T Yokoo - Pediatric Nephrology, 2025 - Springer
Patients with kidney failure require dialysis or kidney transplantation. Kidney transplantation
offers great benefits, including reduced mortality; however, many patients who wish to …

Fetal kidney transplantation for in utero fetuses

K Morimoto, S Yamanaka, K Matsui, Y Kinoshita… - bioRxiv, 2024 - biorxiv.org
Potter sequence, characterized by bilateral renal agenesis, oligohydramnios, and
consequent pulmonary hypoplasia, presents a significant challenge in the management of …