Transposons populate the landscape of all eukaryotic genomes. Often considered purely
genomic parasites, transposons can also benefit their hosts, playing roles in gene regulation …

Transposable elements (TEs) are selfish elements that cause harmful mutations, contribute
to the structure of regulatory networks and shape the architecture of genomes. Natural …

In the Drosophila germline, retrotransposons are silenced by the PIWI-interacting RNA
(piRNA) pathway. Telomeric retroelements HeT-A, TART and TAHRE, which are involved in …

Several recent studies demonstrate that piRNAs guide Piwi protein to repress transposon
transcription in fly ovaries, much as fission yeast use siRNAs to silence repeat sequences …

Successful heterochromatin formation is critical for genome stability in eukaryotes, both to
maintain structures needed for mitosis and meiosis and to silence potentially harmful …

Transposable elements (TEs) are powerful mutagenic agents responsible for generating
variation in the host genome. As TEs can be overtly deleterious, a variety of different …

In the past decade, deep-sequencing approaches have greatly improved our knowledge of
the genome's potential and have become a crucial milestone for new discoveries in …

In the Drosophila germline, retrotransposons are silenced by the PIWI-interacting RNA
(piRNA) pathway. piRNA pathway mutations lead to overexpression and mobilization of …

Сохранение стабильности генома эукариот определяется правильным
формированием гетерохроматина, обеспечивающим сохранность хромосомных …

小RNAs 可以在转录和转录后水**沉默转座子, 最**发现的几类小RNAs (piRNAs, endo-
siRNAs) 均具有抑制转座子活性的作用, 其中, 果蝇piRNAs, 小鼠piRNAs, 小鼠endo-siRNAs …