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[HTML][HTML] Exosome nanovesicles: a potential carrier for therapeutic delivery
Exosomes are small nanosized biovesicles that form when multivesicular bodies and the
plasma membrane fuse and are released into the surrounding body fluids. They are best …
plasma membrane fuse and are released into the surrounding body fluids. They are best …
Activated Drp1 regulates p62-mediated autophagic flux and aggravates inflammation in cerebral ischemia-reperfusion via the ROS-RIP1/RIP3-exosome axis
X Zeng, YD Zhang, RY Ma, YJ Chen, XM **ang… - Military Medical …, 2022 - Springer
Background Cerebral ischemia-reperfusion injury (CIRI) refers to a secondary brain injury
that can occur when the blood supply to the ischemic brain tissue is restored. However, the …
that can occur when the blood supply to the ischemic brain tissue is restored. However, the …
Nanomedicine to target multidrug resistant tumors
Nanomedicine employs nanotechnologies to develop innovative applications, and more
specifically nano-objects in the field of human health, through exploitation of the physical …
specifically nano-objects in the field of human health, through exploitation of the physical …
Engineered exosomes with enhanced stability and delivery efficiency for glioblastoma therapy
Y Wang, Y Huo, C Zhao, H Liu, Y Shao, C Zhu… - Journal of Controlled …, 2024 - Elsevier
Due to the blood-brain barrier (BBB), the application of chemical drugs for glioblastoma
treatment is severely limited. Recently, exosomes have been widely applied for drug …
treatment is severely limited. Recently, exosomes have been widely applied for drug …
Exosomal circ_0030167 derived from BM-MSCs inhibits the invasion, migration, proliferation and stemness of pancreatic cancer cells by sponging miR-338-5p and …
X Yao, Y Mao, D Wu, Y Zhu, J Lu, Y Huang, Y Guo… - Cancer letters, 2021 - Elsevier
Pancreatic cancer (PC) is one of the most lethal malignant tumors and has the lowest
survival rate due to early metastasis and drug resistance. Exosomes derived from bone …
survival rate due to early metastasis and drug resistance. Exosomes derived from bone …
Human breast milk-derived exosomes may help maintain intestinal epithelial barrier integrity
S He, G Liu, X Zhu - Pediatric research, 2021 - nature.com
Background This study explores the functions of exosomes derived from human breast milk
(HBM) in vivo and in vitro. Methods HBM-derived exosomes were collected from healthy …
(HBM) in vivo and in vitro. Methods HBM-derived exosomes were collected from healthy …
Mesenchymal stem cell–originated exosomal circular RNA circFBXW7 attenuates cell proliferation, migration and inflammation of fibroblast-like synoviocytes by …
L Chang, L Kan - Journal of Inflammation Research, 2021 - Taylor & Francis
Background Rheumatoid arthritis (RA) is a chronic autoimmune disease of articular joint
damage and elevated synovial hyperplasia. Abnormal proliferation, invasion inflammatory …
damage and elevated synovial hyperplasia. Abnormal proliferation, invasion inflammatory …
Exosomes in the pathogenesis, progression, and treatment of osteoarthritis
Y Fan, Z Li, Y He - Bioengineering, 2022 - mdpi.com
Osteoarthritis (OA) is a prevalent and debilitating age-related joint disease characterized by
articular cartilage degeneration, synovial membrane inflammation, osteophyte formation, as …
articular cartilage degeneration, synovial membrane inflammation, osteophyte formation, as …
Exosome-based regimen rescues endometrial fibrosis in intrauterine adhesions via targeting clinical fibrosis biomarkers
Y Lin, Y Li, P Chen, Y Zhang, J Sun… - Stem Cells …, 2023 - academic.oup.com
Intrauterine adhesions (IUA), which is characterized by endometrial fibrosis, continue to be
the most common cause of uterine infertility globally. Our work revealed that 3 fibrotic …
the most common cause of uterine infertility globally. Our work revealed that 3 fibrotic …
Hypoxic tumor-derived exosomes induce M2 macrophage polarization via PKM2/AMPK to promote lung cancer progression
S Zhou, Y Lan, Y Li, Z Li, J Pu, L Wei - Cell Transplantation, 2022 - journals.sagepub.com
Hypoxia is a major regulator of tumor aggressiveness and metastasis in cancer progression.
Exosomes (exos) play an important role in the communication between lung cancer and …
Exosomes (exos) play an important role in the communication between lung cancer and …