[HTML][HTML] Exosome nanovesicles: a potential carrier for therapeutic delivery

VP Chavda, A Pandya, L Kumar, N Raval, LK Vora… - Nano Today, 2023 - Elsevier
Exosomes are small nanosized biovesicles that form when multivesicular bodies and the
plasma membrane fuse and are released into the surrounding body fluids. They are best …

Activated Drp1 regulates p62-mediated autophagic flux and aggravates inflammation in cerebral ischemia-reperfusion via the ROS-RIP1/RIP3-exosome axis

X Zeng, YD Zhang, RY Ma, YJ Chen, XM **ang… - Military Medical …, 2022 - Springer
Background Cerebral ischemia-reperfusion injury (CIRI) refers to a secondary brain injury
that can occur when the blood supply to the ischemic brain tissue is restored. However, the …

Nanomedicine to target multidrug resistant tumors

E Lepeltier, P Rijo, F Rizzolio, R Popovtzer… - Drug Resistance …, 2020 - Elsevier
Nanomedicine employs nanotechnologies to develop innovative applications, and more
specifically nano-objects in the field of human health, through exploitation of the physical …

Engineered exosomes with enhanced stability and delivery efficiency for glioblastoma therapy

Y Wang, Y Huo, C Zhao, H Liu, Y Shao, C Zhu… - Journal of Controlled …, 2024 - Elsevier
Due to the blood-brain barrier (BBB), the application of chemical drugs for glioblastoma
treatment is severely limited. Recently, exosomes have been widely applied for drug …

Exosomal circ_0030167 derived from BM-MSCs inhibits the invasion, migration, proliferation and stemness of pancreatic cancer cells by sponging miR-338-5p and …

X Yao, Y Mao, D Wu, Y Zhu, J Lu, Y Huang, Y Guo… - Cancer letters, 2021 - Elsevier
Pancreatic cancer (PC) is one of the most lethal malignant tumors and has the lowest
survival rate due to early metastasis and drug resistance. Exosomes derived from bone …

Human breast milk-derived exosomes may help maintain intestinal epithelial barrier integrity

S He, G Liu, X Zhu - Pediatric research, 2021 - nature.com
Background This study explores the functions of exosomes derived from human breast milk
(HBM) in vivo and in vitro. Methods HBM-derived exosomes were collected from healthy …

Mesenchymal stem cell–originated exosomal circular RNA circFBXW7 attenuates cell proliferation, migration and inflammation of fibroblast-like synoviocytes by …

L Chang, L Kan - Journal of Inflammation Research, 2021 - Taylor & Francis
Background Rheumatoid arthritis (RA) is a chronic autoimmune disease of articular joint
damage and elevated synovial hyperplasia. Abnormal proliferation, invasion inflammatory …

Exosomes in the pathogenesis, progression, and treatment of osteoarthritis

Y Fan, Z Li, Y He - Bioengineering, 2022 - mdpi.com
Osteoarthritis (OA) is a prevalent and debilitating age-related joint disease characterized by
articular cartilage degeneration, synovial membrane inflammation, osteophyte formation, as …

Exosome-based regimen rescues endometrial fibrosis in intrauterine adhesions via targeting clinical fibrosis biomarkers

Y Lin, Y Li, P Chen, Y Zhang, J Sun… - Stem Cells …, 2023 - academic.oup.com
Intrauterine adhesions (IUA), which is characterized by endometrial fibrosis, continue to be
the most common cause of uterine infertility globally. Our work revealed that 3 fibrotic …

Hypoxic tumor-derived exosomes induce M2 macrophage polarization via PKM2/AMPK to promote lung cancer progression

S Zhou, Y Lan, Y Li, Z Li, J Pu, L Wei - Cell Transplantation, 2022 - journals.sagepub.com
Hypoxia is a major regulator of tumor aggressiveness and metastasis in cancer progression.
Exosomes (exos) play an important role in the communication between lung cancer and …