Effect of radiotherapy on T cell and PD-1/PD-L1 blocking therapy in tumor microenvironment
C Chen, Y Liu, B Cui - Human vaccines & immunotherapeutics, 2021 - Taylor & Francis
Cancer is a worldwide problem that threatens human health. Radiotherapy plays an
important role in a variety of cancer treatment methods. The administration of radiotherapy …
important role in a variety of cancer treatment methods. The administration of radiotherapy …
[HTML][HTML] DNA damage enhancement by radiotherapy-activated hafnium oxide nanoparticles improves cGAS-STING pathway activation in human colorectal cancer …
J Marill, NM Anesary, S Paris - Radiotherapy and Oncology, 2019 - Elsevier
The cGAS-STING pathway can be activated by radiation induced DNA damage and
because of its important role in anti-cancer immunity activation, methods to increase its …
because of its important role in anti-cancer immunity activation, methods to increase its …
[HTML][HTML] Vinylphosphonate-based cyclic dinucleotides enhance STING-mediated cancer immunotherapy
M Dejmek, A Brazdova, T Otava, MP Polidarova… - European Journal of …, 2023 - Elsevier
Cyclic dinucleotides (CDNs) trigger the cyclic GMP-AMP synthase-stimulator of interferon
genes (cGAS-STING) pathway, which plays a key role in cytosolic DNA sensing and thus in …
genes (cGAS-STING) pathway, which plays a key role in cytosolic DNA sensing and thus in …
Exogenous DNA enhances DUOX2 expression and function in human pancreatic cancer cells by activating the cGAS-STING signaling pathway
SL Wang, Y Wu, M Konaté, J Lu, D Mallick… - Free Radical Biology …, 2023 - Elsevier
Pro-inflammatory cytokines upregulate the expression of the H 2 O 2-producing NADPH
oxidase dual oxidase 2 (DUOX2) 2 which, when elevated, adversely affects survival from …
oxidase dual oxidase 2 (DUOX2) 2 which, when elevated, adversely affects survival from …
TMEFF2 inhibits pancreatic cancer cells proliferation, migration, and invasion by suppressing phosphorylation of the MAPK signaling pathway
H Han, Z Zhan, J Xu, Z Song - OncoTargets and therapy, 2019 - Taylor & Francis
Purpose This paper studied the effect of TMEFF2 expression on pancreatic cancer and its
mechanism. Methods A total of 72 pancreatic cancer patients were enrolled. AsPC1 and …
mechanism. Methods A total of 72 pancreatic cancer patients were enrolled. AsPC1 and …
Nanoparticle-based Immunotherapeutic Strategies to Target Acute Myeloid Leukemia and Cancer Stem Cells in Melanoma
M Aikins - 2022 - deepblue.lib.umich.edu
Cancer is one of the most prevalent causes of death worldwide, but conventional treatments
including surgical resection, chemotherapy, and radiation therapy have limited efficacy as …
including surgical resection, chemotherapy, and radiation therapy have limited efficacy as …
Exogenous DNA upregulates DUOX2 expression and function in human pancreatic cancer cells by activating the cGAS-STING signaling pathway
SL Wang, Y Wu, M Konaté, J Lu, S Antony, JL Meitzler… - bioRxiv, 2022 - biorxiv.org
Pro-inflammatory cytokines upregulate the expression of the H2O2-producing NADPH
oxidase dual oxidase 2 (DUOX2) which, when elevated, adversely affects survival from …
oxidase dual oxidase 2 (DUOX2) which, when elevated, adversely affects survival from …