Glutamate is the most abundant free amino acid in the brain and is at the crossroad between
multiple metabolic pathways. Considering this, it was a surprise to discover that glutamate …

Disturbances in the glutamatergic system have been increasingly documented in several
neuropsychiatric disorders, including autism spectrum disorder (ASD). Glutamate-centered …

In recent years there has been a growing body of clinical and laboratory evidence
demonstrating the neuroprotective effects of estrogen and progesterone after traumatic brain …

Traumatic brain injury (TBI) has a profound impact on cognitive and mental functioning,
leading to lifelong impairment and significantly diminishing the quality of life for affected …

Autism spectrum disorder (ASD) is a neurodevelopmental disorder based on synaptic
abnormalities. The estimated prevalence rate of male individuals diagnosed with ASD …

Clinical and preclinical research have identified sex differences in substance use and
addiction-related behaviors. Historically, substance use disorders are more prevalent in men …

Chronic use of drugs of abuse affects neuroimmune signaling; however, there are still many
open questions regarding the interactions between neuroimmune mechanisms and …

Melasma is a common acquired hyperpigmentary disorder occurring primarily in photo‐
exposed areas and mainly affecting women of childbearing age. To decipher the role of sex …

Progesterone (P4) is cytoprotective in various experimental models, but our understanding
of the mechanisms involved is still incomplete. Our laboratory has implicated brain-derived …

Metabolomics in human serum samples provide a snapshot of the current metabolic state of
an individuum. Metabolite concentrations are influenced by both genetic and environmental …