Protein design is a valuable tool for understanding the fundamental factors that dictate
protein structure and function. The field of protein design has seen significant progress over …

Zinc is an essential element required for the function of more than 300 enzymes spanning all
classes. Despite years of dedicated study, questions regarding the connections between …

Metalloenzymes efficiently catalyze some of the most important and difficult reactions in
nature. For many years, coordination chemists have effectively used small molecule models …

About 50% of the 1.4 GeV CERN (European Organization for Nuclear Research, www. cern.
ch) protons are sent onto targets to produce radioactive beams by online mass separation at …

Arsenic is highly toxic and a significant threat to human health, but certain bacteria have
developed defense mechanisms initiated by AsIII binding to AsIII-sensing proteins of the …

While metalloprotein design has now yielded a number of successful metal-bound and even
catalytically active constructs, the question of where to put a metal site along a linear …

An important objective of de novo protein design is the preparation of metalloproteins, as
many natural systems contain metals that play crucial roles for the function and/or structural …

The electrostatic contribution to the Mössbauer isomer shift of mercury for the series HgF n
(n= 1, 2, 4) with respect to the neutral atom has been investigated in the framework of four …

Conspectus The major advances in molecular and structural biology and automated peptide
and DNA synthesis of the 1970s and 1980s generated fertile conditions in the 1990s for the …

Time differential perturbed angular correlation (TDPAC) of γ-rays spectroscopy has been
applied in chemistry and biochemistry for decades. Herein we aim to present a …