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Methods of model reduction for large-scale biological systems: a survey of current methods and trends
TJ Snowden, PH van der Graaf, MJ Tindall - Bulletin of mathematical …, 2017 - Springer
Complex models of biochemical reaction systems have become increasingly common in the
systems biology literature. The complexity of such models can present a number of …
systems biology literature. The complexity of such models can present a number of …
[PDF][PDF] Moving from postdictive to predictive kinetics in reaction engineering
WH Green - 2020 - dspace.mit.edu
Accurate quantitative chemical kinetic models are useful in many applications, ranging from
design of chemical processes to building a consensus for international treaties (eg the …
design of chemical processes to building a consensus for international treaties (eg the …
Dynamics and control of an ethyl acetate reactive distillation column
N Vora, P Daoutidis - Industrial & engineering chemistry research, 2001 - ACS Publications
In this paper, we study the dynamics and control of a reactive distillation column for the
production of ethyl acetate from acetic acid and ethyl alcohol. Initially, we propose a …
production of ethyl acetate from acetic acid and ethyl alcohol. Initially, we propose a …
Experimental design and model reduction in systems biology
JE Jeong, Q Zhuang, MK Transtrum… - Quantitative …, 2018 - Wiley Online Library
Background In systems biology, the dynamics of biological networks are often modeled with
ordinary differential equations (ODEs) that encode interacting components in the systems …
ordinary differential equations (ODEs) that encode interacting components in the systems …
Modelling the impact of mass transport in a miniplant photoreactor
F Gaulhofer, H Becker, A Peschl… - Reaction Chemistry & …, 2024 - pubs.rsc.org
The scale-up of photoreactions posses challenges due to the non-linear coupling of the
radiation field with reaction kinetics and mass transport. A knowledge-based scale-up …
radiation field with reaction kinetics and mass transport. A knowledge-based scale-up …
Direct olivine carbonation: Optimal process design for a low-emission and cost-efficient cement production
Employing mineral carbonation products as a cementitious substitute could reduce the
cement industry's greenhouse gas (GHG) emissions. However, a transition toward low …
cement industry's greenhouse gas (GHG) emissions. However, a transition toward low …
Algorithmic criteria for the validity of quasi-steady state and partial equilibrium models: The Michaelis–Menten reaction mechanism
DG Patsatzis, DA Goussis - Journal of Mathematical Biology, 2023 - Springer
We present “on the fly” algorithmic criteria for the accuracy and stability (non-stiffness) of
reduced models constructed with the quasi-steady state and partial equilibrium …
reduced models constructed with the quasi-steady state and partial equilibrium …
Extents of reaction and flow for homogeneous reaction systems with inlet and outlet streams
For homogeneous reaction systems with inlet and outlet streams, this article proposes a
linear transformation of the number of moles vector into three distinct parts, namely, the …
linear transformation of the number of moles vector into three distinct parts, namely, the …
Non-linear reduction for kinetic models of metabolic reaction networks
Kinetic models of metabolic networks are essential for predicting and optimizing the
transient behavior of cells in culture. However, such models are inherently high dimensional …
transient behavior of cells in culture. However, such models are inherently high dimensional …
Asymptotology of chemical reaction networks
The concept of the limiting step is extended to the asymptotology of multiscale reaction
networks. Complete theory for linear networks with well separated reaction rate constants is …
networks. Complete theory for linear networks with well separated reaction rate constants is …