Emerging links between cerebrovascular and neurodegenerative diseases—a special role for pericytes

U Lendahl, P Nilsson, C Betsholtz - EMBO reports, 2019 - embopress.org
Neurodegenerative and cerebrovascular diseases cause considerable human suffering,
and therapy options for these two disease categories are limited or non‐existing. It is an …

Post-COVID exercise intolerance is associated with capillary alterations and immune dysregulations in skeletal muscles

T Aschman, E Wyler, O Baum, A Hentschel… - Acta Neuropathologica …, 2023 - Springer
The SARS-CoV-2 pandemic not only resulted in millions of acute infections worldwide, but
also in many cases of post-infectious syndromes, colloquially referred to as “long COVID” …

Comparison of the behavior of perivascular cells (pericytes and cd34+ stromal cell/telocytes) in sprouting and intussusceptive angiogenesis

L Díaz-Flores, R Gutiérrez, MP García… - International Journal of …, 2022 - mdpi.com
Perivascular cells in the pericytic microvasculature, pericytes and CD34+ stromal
cells/telocytes (CD34+ SCs/TCs), have an important role in angiogenesis. We compare the …

The effect of two exercise modalities on skeletal muscle capillary ultrastructure in individuals with type 2 diabetes

SP Mortensen, KM Winding, UW Iepsen… - … journal of medicine …, 2019 - Wiley Online Library
Type 2 diabetes is associated with microvascular dysfunction, but little is known about how
capillary ultrastructure is affected by exercise training. To investigate the effect of two types …

Muscle proteomic and transcriptomic profiling of healthy aging and metabolic syndrome in men

M Gueugneau, C Coudy-Gandilhon… - International Journal of …, 2021 - mdpi.com
(1) Background: Aging is associated with a progressive decline in muscle mass and
function. Aging is also a primary risk factor for metabolic syndrome, which further alters …

The role of muscle perfusion in the age-associated decline of mitochondrial function in healthy individuals

F Adelnia, D Cameron, CM Bergeron… - Frontiers in …, 2019 - frontiersin.org
Maximum oxidative capacity of skeletal muscle measured by in vivo phosphorus magnetic
resonance spectroscopy (31P-MRS) declines with age, and negatively affects whole-body …

Pericapillary basement membrane thickening in human skeletal muscles

O Baum, M Bigler - American Journal of Physiology-Heart …, 2016 - journals.physiology.org
The basement membrane (BM) surrounding capillaries in skeletal muscles varies
physiologically in thickness according to age, physical fitness, and anatomical site in …

Post-COVID syndrome is associated with capillary alterations, macrophage infiltration and distinct transcriptomic signatures in skeletal muscles

T Aschman, E Wyler, O Baum, A Hentschel, F Legler… - MedRxiv, 2023 - medrxiv.org
The SARS-CoV-2 pandemic not only resulted in millions of acute infections worldwide, but
also caused innumerable cases of post-infectious syndromes, colloquially referred to as …

Structural microangiopathies in skeletal muscle related to systemic vascular pathologies in humans

O Baum, J Bernd, S Becker, A Odriozola… - Frontiers in …, 2020 - frontiersin.org
It is unclear how microangiopathic changes in skeletal muscle vary among systemic
vascular pathologies. We therefore analyzed the capillary fine structure in skeletal muscle …

Capillary facilitation of skeletal muscle function in health and disease

G Parise, CL Murrant, M Cocks… - Applied Physiology …, 2020 - cdnsciencepub.com
Skeletal muscle is highly vascularized, with perfusion being tightly regulated to meet wide-
ranging metabolic demands. For decades, the capillary supply has been explored mainly in …