Emerging links between cerebrovascular and neurodegenerative diseases—a special role for pericytes
Neurodegenerative and cerebrovascular diseases cause considerable human suffering,
and therapy options for these two disease categories are limited or non‐existing. It is an …
and therapy options for these two disease categories are limited or non‐existing. It is an …
Post-COVID exercise intolerance is associated with capillary alterations and immune dysregulations in skeletal muscles
T Aschman, E Wyler, O Baum, A Hentschel… - Acta Neuropathologica …, 2023 - Springer
The SARS-CoV-2 pandemic not only resulted in millions of acute infections worldwide, but
also in many cases of post-infectious syndromes, colloquially referred to as “long COVID” …
also in many cases of post-infectious syndromes, colloquially referred to as “long COVID” …
Comparison of the behavior of perivascular cells (pericytes and cd34+ stromal cell/telocytes) in sprouting and intussusceptive angiogenesis
L Díaz-Flores, R Gutiérrez, MP García… - International Journal of …, 2022 - mdpi.com
Perivascular cells in the pericytic microvasculature, pericytes and CD34+ stromal
cells/telocytes (CD34+ SCs/TCs), have an important role in angiogenesis. We compare the …
cells/telocytes (CD34+ SCs/TCs), have an important role in angiogenesis. We compare the …
The effect of two exercise modalities on skeletal muscle capillary ultrastructure in individuals with type 2 diabetes
Type 2 diabetes is associated with microvascular dysfunction, but little is known about how
capillary ultrastructure is affected by exercise training. To investigate the effect of two types …
capillary ultrastructure is affected by exercise training. To investigate the effect of two types …
Muscle proteomic and transcriptomic profiling of healthy aging and metabolic syndrome in men
M Gueugneau, C Coudy-Gandilhon… - International Journal of …, 2021 - mdpi.com
(1) Background: Aging is associated with a progressive decline in muscle mass and
function. Aging is also a primary risk factor for metabolic syndrome, which further alters …
function. Aging is also a primary risk factor for metabolic syndrome, which further alters …
The role of muscle perfusion in the age-associated decline of mitochondrial function in healthy individuals
Maximum oxidative capacity of skeletal muscle measured by in vivo phosphorus magnetic
resonance spectroscopy (31P-MRS) declines with age, and negatively affects whole-body …
resonance spectroscopy (31P-MRS) declines with age, and negatively affects whole-body …
Pericapillary basement membrane thickening in human skeletal muscles
O Baum, M Bigler - American Journal of Physiology-Heart …, 2016 - journals.physiology.org
The basement membrane (BM) surrounding capillaries in skeletal muscles varies
physiologically in thickness according to age, physical fitness, and anatomical site in …
physiologically in thickness according to age, physical fitness, and anatomical site in …
Post-COVID syndrome is associated with capillary alterations, macrophage infiltration and distinct transcriptomic signatures in skeletal muscles
T Aschman, E Wyler, O Baum, A Hentschel, F Legler… - MedRxiv, 2023 - medrxiv.org
The SARS-CoV-2 pandemic not only resulted in millions of acute infections worldwide, but
also caused innumerable cases of post-infectious syndromes, colloquially referred to as …
also caused innumerable cases of post-infectious syndromes, colloquially referred to as …
Structural microangiopathies in skeletal muscle related to systemic vascular pathologies in humans
O Baum, J Bernd, S Becker, A Odriozola… - Frontiers in …, 2020 - frontiersin.org
It is unclear how microangiopathic changes in skeletal muscle vary among systemic
vascular pathologies. We therefore analyzed the capillary fine structure in skeletal muscle …
vascular pathologies. We therefore analyzed the capillary fine structure in skeletal muscle …
Capillary facilitation of skeletal muscle function in health and disease
G Parise, CL Murrant, M Cocks… - Applied Physiology …, 2020 - cdnsciencepub.com
Skeletal muscle is highly vascularized, with perfusion being tightly regulated to meet wide-
ranging metabolic demands. For decades, the capillary supply has been explored mainly in …
ranging metabolic demands. For decades, the capillary supply has been explored mainly in …