COVID-19: drug targets and potential treatments

C Gil, T Ginex, I Maestro, V Nozal… - Journal of medicinal …, 2020 - ACS Publications
Currently, humans are immersed in a pandemic caused by the emerging severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), which threatens public health …

SARS-CoV-2 Mpro: A Potential Target for Peptidomimetics and Small-Molecule Inhibitors

A Citarella, A Scala, A Piperno, N Micale - Biomolecules, 2021 - mdpi.com
The uncontrolled spread of the COVID-19 pandemic caused by the new coronavirus SARS-
CoV-2 during 2020–2021 is one of the most devastating events in the history, with …

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2): a global pandemic and treatment strategies

A Sharma, S Tiwari, MK Deb, JL Marty - International journal of antimicrobial …, 2020 - Elsevier
The emergence and rapid spread of coronavirus disease 2019 (COVID-19), caused by
severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), a potentially fatal disease …

Drugs repurposed for COVID-19 by virtual screening of 6,218 drugs and cell-based assay

WD Jang, S Jeon, S Kim, SY Lee - … of the National Academy of Sciences, 2021 - pnas.org
The COVID-19 pandemic caused by SARS-CoV-2 is an unprecedentedly significant health
threat, prompting the need for rapidly develo** antiviral drugs for the treatment. Drug …

Identification of potential molecules against COVID-19 main protease through structure-guided virtual screening approach

L Mittal, A Kumari, M Srivastava, M Singh… - Journal of …, 2021 - Taylor & Francis
The pandemic caused by novel coronavirus disease 2019 (COVID-19) infecting millions of
populations worldwide and counting, has demanded quick and potential therapeutic …

Catechin and curcumin interact with S protein of SARS-CoV2 and ACE2 of human cell membrane: insights from computational studies

AB Jena, N Kanungo, V Nayak, GBN Chainy… - Scientific reports, 2021 - nature.com
The recent outbreak of the coronavirus (SARS-CoV2) is an unprecedented threat to human
health and society across the globe. In this context, development of suitable interventions is …

A review on drug repurposing applicable to COVID-19

S Dotolo, A Marabotti, A Facchiano… - Briefings in …, 2021 - academic.oup.com
Drug repurposing involves the identification of new applications for existing drugs at a lower
cost and in a shorter time. There are different computational drug-repurposing strategies and …

Recent review of COVID-19 management: Diagnosis, treatment and vaccination

VP Chavda, S Vuppu, T Mishra, S Kamaraj… - Pharmacological …, 2022 - Springer
The idiopathic Coronavirus disease 2019 (COVID-19) pandemic outbreak caused by the
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has reached global …

COVID-19: Review on latest available drugs and therapies against SARS-CoV-2. Coagulation and inflammation cross-talking

G Magro - Virus research, 2020 - Elsevier
SARS-CoV-2 is the agent responsible for COVID-19. The infection can be dived into three
phases: mild infection, the pulmonary phase and the inflammatory phase. Treatment options …

[HTML][HTML] Quantitative structure-property relationships (QSPR) of valency based topological indices with Covid-19 drugs and application

JF Zhong, A Rauf, M Naeem, J Rahman… - Arabian Journal of …, 2021 - Elsevier
The purpose of this analysis is to establish a quantitative structure–property relationship
(QSPR) between eV and ve-degree based topological descriptors and measured …