'Function'is the key criterion for determining whether adult neurogenesis—be it endogenous,
induced, or after transplantation—is successful and has truly generated new nerve cells …

Embryonic stem cells have huge potential in the field of tissue engineering and regenerative
medicine as they hold the capacity to produce every type of cell and tissue in the body. In …

Adult hippocampal neurogenesis is considered important for cognition. The integration of
newborn dentate gyrus granule cells into the existing network is regulated by afferent …

Mesenchymal stem cells (MSCs) are adult stem cells that were initially isolated from bone
marrow. However, subsequent research has shown that other adult tissues also contain …

How a naive human neuroepithelial cell becomes an electrophysiologically active neuron
remains unknown. Here, we describe the early physiological development of neurons …

The optogenetic approach to gain control over neuronal excitability both in vitro and in vivo
has emerged as a fascinating scientific tool to explore neuronal networks, but it also opens …

The retina in adult mammals, unlike those in lower vertebrates such as fish and amphibians,
is not known to support neurogenesis. However, when injured, the adult mammalian retina …

Given their accessibility, multipotent skin-derived cells might be useful for future cell
replacement therapies. We describe the isolation of multipotent stem cell–like cells from the …

Cells that express the NG2 proteoglycan are the largest proliferative progenitor population in
the postnatal central nervous system (CNS). Although this entire population has long been …

Stroke represents one of the leading causes of death and disability in Western countries, but
despite intense research, only few options exist for the treatment of stroke-related infarction …