Click chemistry and radiochemistry: an update

D Bauer, MA Cornejo, TT Hoang, JS Lewis… - Bioconjugate …, 2023 - ACS Publications
The term “click chemistry” describes a class of organic transformations that were developed
to make chemical synthesis simpler and easier, in essence allowing chemists to combine …

Nonlinear optical properties of emerging nano‐and microcrystalline materials

JK Zaręba, M Nyk, M Samoć - Advanced Optical Materials, 2021 - Wiley Online Library
The activity in the research on novel optical materials exhibiting nonlinear optical (NLO)
properties is surveyed, especially nonlinear absorption, that may be attractive for various …

Recent advances in bioorthogonal click chemistry for enhanced PET and SPECT radiochemistry

X Zhong, J Yan, X Ding, C Su, Y Xu… - Bioconjugate …, 2023 - ACS Publications
Due to their high reaction rate and reliable selectivity, bioorthogonal click reactions have
been extensively investigated in numerous research fields, such as nanotechnology, drug …

Click chemistry approaches for develo** carbonic anhydrase inhibitors and their applications

A Angeli, CT Supuran - Journal of Enzyme Inhibition and Medicinal …, 2023 - Taylor & Francis
Click chemistry reactions constitute an important and relatively new approach in the
medicinal chemistry toolbox and offer substantial advantages to medicinal chemists in terms …

From molecules to medicine: thiol selective bioconjugation in synthesis of diagnostic and therapeutic radiopharmaceuticals

I Bibi, S Mushtaq, KC Lee, JA Park, JY Kim - Theranostics, 2024 - pmc.ncbi.nlm.nih.gov
Radiolabeling of biomolecules and cells with radiolabeled prosthetic groups has significant
implications for nuclear medicine, imaging, and radiotherapy. Achieving site-specific and …

Recent advances in bioorthogonal click chemistry for efficient synthesis of radiotracers and radiopharmaceuticals

S Mushtaq, SJ Yun, J Jeon - Molecules, 2019 - mdpi.com
In recent years, several catalyst-free site-specific reactions have been investigated for the
efficient conjugation of biomolecules, nanomaterials, and living cells. Representative …

A comparison study of fiber diameter's effect on characteristic features of donepezil/curcumin‐loaded polycaprolactone/polylactic acid nanofibers

S Aydin, I Kabaoglu, E Guler, F Topal… - Macromolecular …, 2022 - Wiley Online Library
Nanofibers (NFs) offer an alternative option for the treatment of Alzheimer's disease (AD) by
addressing unmet clinical problems. In this study, anti‐AD drugs, donepezil (DO) and …

[HTML][HTML] New developments in carbonic anhydrase IX-targeted fluorescence and nuclear imaging agents

KT Chen, Y Seimbille - International Journal of Molecular Sciences, 2022 - mdpi.com
Carbonic anhydrase IX (CAIX) is a tumor-specific and hypoxia-induced biomarker for the
molecular imaging of solid malignancies. The nuclear-and optical-imaging of CAIX …

Advances in development of radiometal labeled amino acid-based compounds for cancer imaging and diagnostics

MB Mikulová, P Mikuš - Pharmaceuticals, 2021 - mdpi.com
Radiolabeled biomolecules targeted at tumor-specific enzymes, receptors, and transporters
in cancer cells represent an intensively investigated and promising class of molecular tools …

Preclinical Evaluation of a PSMA-Targeting Homodimer with an Optimized Linker for Imaging of Prostate Cancer

E Murce, S Beekman, E Spaan, M Handula… - Molecules, 2023 - mdpi.com
Prostate-specific membrane antigen (PSMA) targeting radiopharmaceuticals have been
successfully used for diagnosis and therapy of prostate cancer. Optimization of the available …