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CRISPR–Cas9 gRNA efficiency prediction: an overview of predictive tools and the role of deep learning
The clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated
protein 9 (Cas9) system has become a successful and promising technology for gene …
protein 9 (Cas9) system has become a successful and promising technology for gene …
[HTML][HTML] Latest developed strategies to minimize the off-target effects in CRISPR-Cas-mediated genome editing
Gene editing that makes target gene modification in the genome by deletion or addition has
revolutionized the era of biomedicine. Clustered regularly interspaced short palindromic …
revolutionized the era of biomedicine. Clustered regularly interspaced short palindromic …
Plant breeding advancements with “CRISPR-Cas” genome editing technologies will assist future food security
M Ahmad - Frontiers in plant science, 2023 - frontiersin.org
Genome editing techniques are being used to modify plant breeding, which might increase
food production sustainably by 2050. A product made feasible by genome editing is …
food production sustainably by 2050. A product made feasible by genome editing is …
Applications and challenges of CRISPR-Cas gene-editing to disease treatment in clinics
W Liu, L Li, J Jiang, M Wu, P Lin - Precision clinical medicine, 2021 - academic.oup.com
Clustered regularly interspaced short palindromic repeats (CRISPR)-associated systems
(Cas) are efficient tools for targeting specific genes for laboratory research, agricultural …
(Cas) are efficient tools for targeting specific genes for laboratory research, agricultural …
CRISPR/Cas9 gene editing: a new approach for overcoming drug resistance in cancer
M Vaghari-Tabari, P Hassanpour… - Cellular & Molecular …, 2022 - Springer
The CRISPR/Cas9 system is an RNA-based adaptive immune system in bacteria and
archaea. Various studies have shown that it is possible to target a wide range of human …
archaea. Various studies have shown that it is possible to target a wide range of human …
Current bioinformatics tools to optimize CRISPR/Cas9 experiments to reduce off-target effects
M Naeem, OS Alkhnbashi - International Journal of Molecular Sciences, 2023 - mdpi.com
The CRISPR-Cas system has evolved into a cutting-edge technology that has transformed
the field of biological sciences through precise genetic manipulation. CRISPR/Cas9 …
the field of biological sciences through precise genetic manipulation. CRISPR/Cas9 …
Genome editing and beyond: what does it mean for the future of plant breeding?
Main conclusion Genome editing offers revolutionized solutions for plant breeding to sustain
food production to feed the world by 2050. Therefore, genome-edited products are …
food production to feed the world by 2050. Therefore, genome-edited products are …
CRISPR interference screens reveal growth–robustness tradeoffs in Synechocystis sp. PCC 6803 across growth conditions
Barcoded mutant libraries are a powerful tool for elucidating gene function in microbes,
particularly when screened in multiple growth conditions. Here, we screened a pooled …
particularly when screened in multiple growth conditions. Here, we screened a pooled …
Using traditional machine learning and deep learning methods for on-and off-target prediction in CRISPR/Cas9: a review
Abstract CRISPR/Cas9 (Clustered Regularly Interspaced Short Palindromic Repeats and
CRISPR-associated protein 9) is a popular and effective two-component technology used for …
CRISPR-associated protein 9) is a popular and effective two-component technology used for …
[HTML][HTML] CRISPR-Cas9 system for plant genome editing: current approaches and emerging developments
Targeted genome editing using CRISPR-Cas9 has been widely adopted as a genetic
engineering tool in various biological systems. This editing technology has been in the …
engineering tool in various biological systems. This editing technology has been in the …