Radiotherapy toxicity

D De Ruysscher, G Niedermann, NG Burnet… - Nature reviews Disease …, 2019‏ - nature.com
Radiotherapy is used in> 50% of patients with cancer, both for curative and palliative
purposes. Radiotherapy uses ionizing radiation to target and kill tumour tissue, but normal …

Radiation-induced lung injury (RILI)

L Giuranno, J Ient, D De Ruysscher, MA Vooijs - Frontiers in oncology, 2019‏ - frontiersin.org
Radiation pneumonitis (RP) and radiation fibrosis (RF) are two dose-limiting toxicities of
radiotherapy (RT), especially for lung, and esophageal cancer. It occurs in 5–20% of …

Imaging-based target volume reduction in chemoradiotherapy for locally advanced non-small-cell lung cancer (PET-Plan): a multicentre, open-label, randomised …

U Nestle, T Schimek-Jasch, S Kremp… - The Lancet …, 2020‏ - thelancet.com
Background With increasingly precise radiotherapy and advanced medical imaging, the
concept of radiotherapy target volume planning might be redefined with the aim of improving …

Radiation-induced lung toxicity–cellular and molecular mechanisms of pathogenesis, management, and literature review

L Käsmann, A Dietrich, CA Staab-Weijnitz… - Radiation …, 2020‏ - Springer
Lung, breast, and esophageal cancer represent three common malignancies with high
incidence and mortality worldwide. The management of these tumors critically relies on …

Technological quality requirements for stereotactic radiotherapy: Expert review group consensus from the DGMP Working Group for Physics and Technology in …

D Schmitt, O Blanck, T Gauer, MK Fix… - Strahlentherapie und …, 2020‏ - Springer
This review details and discusses the technological quality requirements to ensure the
desired quality for stereotactic radiotherapy using photon external beam radiotherapy as …

ESTRO ACROP guidelines for target volume definition in the treatment of locally advanced non-small cell lung cancer

U Nestle, D De Ruysscher, U Ricardi, X Geets… - Radiotherapy and …, 2018‏ - Elsevier
Radiotherapy (RT) plays a major role in the curative treatment of locally advanced non-small
cell lung cancer (NSCLC). Therefore, the ACROP committee was asked by the ESTRO to …

The evolving role of radiotherapy in non-small cell lung cancer

S Brown, K Banfill, MC Aznar… - The British journal of …, 2019‏ - academic.oup.com
Lung cancer is the most commonly diagnosed cancer and biggest cause of cancer mortality
worldwide with non-small cell lung cancer (NSCLC) accounting for most cases …

ESTRO ACROP consensus guideline on implementation and practice of stereotactic body radiotherapy for peripherally located early stage non-small cell lung cancer

M Guckenberger, N Andratschke, K Dieckmann… - Radiotherapy and …, 2017‏ - Elsevier
Background Stereotactic body radiotherapy (SBRT) has become the standard of care for
medically inoperable patients with peripherally located, early stage non-small cell lung …

[HTML][HTML] Tackling the current dilemma of immunotherapy in extensive-stage small cell lung cancer: A promising strategy of combining with radiotherapy

K Kang, Y Wu, Z Yao, Y Lu - Cancer Letters, 2023‏ - Elsevier
Progress in the treatment of small cell lung cancer (SCLC) has been modest over the past
decades until the advent of immune checkpoint inhibitors, which have redefined the …

[HTML][HTML] Recommendation for supportive care in patients receiving concurrent chemotherapy and radiotherapy for lung cancer

D De Ruysscher, C Faivre-Finn, K Nackaerts… - Annals of …, 2020‏ - Elsevier
Highlights•Supportive care is an integral part of CCRT.•All aspects are important.•A multi-
disciplinary approach is mandatory.Concurrent chemotherapy and radiotherapy (CCRT) …