With the passage of time, people step toward old age and become more prone to several
diseases associated with the age. One such is Alzheimer's disease (AD) which results into …

Alzheimer's disease (AD) is one of the most common age-related neurodegenerative
disorders that have been studied for more than 100 years. Although an increased level of …

Intracellular zinc accumulation has been shown to be associated with neuronal death after
cerebral ischemia. However, the mechanism of zinc accumulation leading to neuronal death …

Zinc transporter 3 (ZnT3) is abundantly expressed in the brain, residing in synaptic vesicles,
where it plays important roles in controlling the luminal zinc levels. In this study, we found …

Vision depends on accurate signal conduction from the retina to the brain through the optic
nerve, an important part of the central nervous system that consists of bundles of axons …

Simple Summary An early time course study of the proteins associated to synaptic dynamics
and cognitive behavior. Study evaluated the expression levels and activation state of …

Oxidative stress, induced by impaired insulin signaling in the brain contributes to cognitive
loss in sporadic Alzheimer's disease (sAD). This study evaluated early hippocampal …

Introduction Increasing epidemiological evidence highlights the association between
systemic insulin resistance and Alzheimer's disease (AD). It is known that peripheral insulin …

Background: Alzheimer's disease (AD) is a neurodegenerative and progressive disorder
with no cure and constant failures in clinical trials. The main AD hallmarks are amyloid-β …

Metabolic dysfunction is a critical step in the etiopathogenesis of Alzheimer's disease. In this
progressive neurological disorder, impaired zinc homeostasis has a key role that needs to …