[HTML][HTML] Physiology of cholangiocytes
JH Tabibian, AI Masyuk, TV Masyuk… - Comprehensive …, 2013 - ncbi.nlm.nih.gov
Cholangiocytes are epithelial cells that line the intra-and extrahepatic ducts of the biliary
tree. The main physiologic function of cholangiocytes is modification of hepatocyte-derived …
tree. The main physiologic function of cholangiocytes is modification of hepatocyte-derived …
Pathogenesis of cholestatic liver disease and therapeutic approaches
GM Hirschfield, EJ Heathcote, ME Gershwin - Gastroenterology, 2010 - Elsevier
Cholestatic liver disorders are caused by genetic defects, mechanical aberrations, toxins, or
dysregulations in the immune system that damage the bile ducts and cause accumulation of …
dysregulations in the immune system that damage the bile ducts and cause accumulation of …
[HTML][HTML] Functional and structural features of cholangiocytes in health and disease
Cholangiocytes are the epithelial cells that line the bile ducts. Along the biliary tree, two
different kinds of cholangiocytes exist: small and large cholangiocytes. Each type has …
different kinds of cholangiocytes exist: small and large cholangiocytes. Each type has …
Role of docosahexaenoic acid treatment in improving liver histology in pediatric nonalcoholic fatty liver disease
Introduction Nonalcoholic fatty liver disease (NAFLD) is one of the most important causes of
liver-related morbidity and mortality in children. Recently, we have reported the effects of …
liver-related morbidity and mortality in children. Recently, we have reported the effects of …
[PDF][PDF] The secretin/secretin receptor axis modulates liver fibrosis through changes in transforming growth factor‐β1 biliary secretion in mice
The secretin/secretin receptor (SR) axis is up‐regulated by proliferating cholangiocytes
during cholestasis. Secretin stimulates biliary proliferation by down‐regulation of let‐7a and …
during cholestasis. Secretin stimulates biliary proliferation by down‐regulation of let‐7a and …
[HTML][HTML] The physiological roles of secretin and its receptor
S Afroze, F Meng, K Jensen, K McDaniel… - Annals of …, 2013 - ncbi.nlm.nih.gov
Secretin is secreted by S cells in the small intestine and affects the function of a number of
organ systems. Secretin receptors (SR) are expressed in the basolateral domain of several …
organ systems. Secretin receptors (SR) are expressed in the basolateral domain of several …
[HTML][HTML] Mechanisms of cholangiocyte responses to injury
Cholangiocytes, epithelial cells that line the biliary epithelium, are the primary target cells for
cholangiopathies including primary sclerosing cholangitis and primary biliary cholangitis …
cholangiopathies including primary sclerosing cholangitis and primary biliary cholangitis …
Stem/progenitor cell niches involved in hepatic and biliary regeneration
G Carpino, A Renzi, A Franchitto… - Stem Cells …, 2016 - Wiley Online Library
Niches containing stem/progenitor cells are present in different anatomical locations along
the human biliary tree and within liver acini. The most primitive stem/progenitors, biliary tree …
the human biliary tree and within liver acini. The most primitive stem/progenitors, biliary tree …
Secretin stimulates biliary cell proliferation by regulating expression of microRNA 125b and microRNA let7a in mice
Background & Aims Proliferating cholangiocytes secrete and respond to neuroendocrine
hormones, including secretin. We investigated whether secretin secreted by S cells and …
hormones, including secretin. We investigated whether secretin secreted by S cells and …
Recent advances in the morphological and functional heterogeneity of the biliary epithelium
This review focuses on the recent advances related to the heterogeneity of different-sized
bile ducts with regard to the morphological and phenotypical characteristics, and the …
bile ducts with regard to the morphological and phenotypical characteristics, and the …