Short-chain fatty-acid-producing bacteria: key components of the human gut microbiota

W Fusco, MB Lorenzo, M Cintoni, S Porcari… - Nutrients, 2023 - mdpi.com
Short-chain fatty acids (SCFAs) play a key role in health and disease, as they regulate gut
homeostasis and their deficiency is involved in the pathogenesis of several disorders …

Obesity and type 2 diabetes mellitus: connections in epidemiology, pathogenesis, and treatments

R Ruze, T Liu, X Zou, J Song, Y Chen, R Xu… - Frontiers in …, 2023 - frontiersin.org
The prevalence of obesity and diabetes mellitus (DM) has been consistently increasing
worldwide. Sharing powerful genetic and environmental features in their pathogenesis …

[HTML][HTML] Gut microbiome and health: mechanistic insights

WM De Vos, H Tilg, M Van Hul, PD Cani - Gut, 2022 - gut.bmj.com
The gut microbiota is now considered as one of the key elements contributing to the
regulation of host health. Virtually all our body sites are colonised by microbes suggesting …

[HTML][HTML] Gut bacteria and neurotransmitters

LMT Dicks - Microorganisms, 2022 - mdpi.com
Gut bacteria play an important role in the digestion of food, immune activation, and
regulation of entero-endocrine signaling pathways, but also communicate with the central …

Inter-organ crosstalk during development and progression of type 2 diabetes mellitus

G Xourafa, M Korbmacher, M Roden - Nature Reviews Endocrinology, 2024 - nature.com
Type 2 diabetes mellitus (T2DM) is characterized by tissue-specific insulin resistance and
pancreatic β-cell dysfunction, which result from the interplay of local abnormalities within …

[HTML][HTML] Postbiotics: current trends in food and pharmaceutical industry

P Thorakkattu, AC Khanashyam, K Shah, KS Babu… - Foods, 2022 - mdpi.com
Postbiotics are non-viable bacterial products or metabolic byproducts produced by probiotic
microorganisms that have biologic activity in the host. Postbiotics are functional bioactive …

Akkermansia muciniphila and Gut Immune System: A Good Friendship That Attenuates Inflammatory Bowel Disease, Obesity, and Diabetes

VF Rodrigues, J Elias-Oliveira, ÍS Pereira… - Frontiers in …, 2022 - frontiersin.org
Akkermansia muciniphila is a Gram-negative anaerobic mucus-layer-degrading bacterium
that colonizes the intestinal mucosa of humans and rodents. Metagenomic data have shown …

Signalling cognition: The gut microbiota and hypothalamic-pituitary-adrenal axis

JA Rusch, BT Layden, LR Dugas - Frontiers in endocrinology, 2023 - frontiersin.org
Cognitive function in humans depends on the complex and interplay between multiple body
systems, including the hypothalamic-pituitary-adrenal (HPA) axis. The gut microbiota, which …

Short chain fatty acids: Microbial metabolites for gut-brain axis signalling

KJ O'Riordan, MK Collins, GM Moloney… - Molecular and Cellular …, 2022 - Elsevier
The role of the intestinal microbiota as a regulator of gut-brain axis signalling has risen to
prominence in recent years. Understanding the relationship between the gut microbiota, the …

Regulation of neurotransmitters by the gut microbiota and effects on cognition in neurological disorders

Y Chen, J Xu, Y Chen - Nutrients, 2021 - mdpi.com
Emerging evidence indicates that gut microbiota is important in the regulation of brain
activity and cognitive functions. Microbes mediate communication among the metabolic …