Lupus nephritis

HJ Anders, R Saxena, M Zhao, I Parodis… - Nature reviews Disease …, 2020 - nature.com
Lupus nephritis (LN) is a form of glomerulonephritis that constitutes one of the most severe
organ manifestations of the autoimmune disease systemic lupus erythematosus (SLE). Most …

Lupus nephritis: clinical presentations and outcomes in the 21st century

M Gasparotto, M Gatto, V Binda, A Doria… - Rheumatology, 2020 - academic.oup.com
Lupus nephritis (LN) is a frequent and severe manifestation of SLE. Along the decades, the
epidemiology of LN and its clinical presentation have been changing. However, even …

KDIGO 2021 clinical practice guideline for the management of glomerular diseases

BH Rovin, SG Adler, J Barratt, F Bridoux… - Kidney …, 2021 - kidney-international.org
Glomerular disease, be it primary or secondary, occurring in the setting of systemic
autoimmune diseases, infections, drugs, or malignancy, affects individuals of all ages. In …

2019 update of the EULAR recommendations for the management of systemic lupus erythematosus

A Fanouriakis, M Kostopoulou, A Alunno… - Annals of the …, 2019 - ard.bmj.com
Our objective was to update the EULAR recommendations for the management of systemic
lupus erythematosus (SLE), based on emerging new evidence. We performed a systematic …

American College of Rheumatology guidelines for screening, treatment, and management of lupus nephritis

BH Hahn, MA Mcmahon, A Wilkinson… - Arthritis care & …, 2012 - Wiley Online Library
In the US, approximately 35% of adults with systemic lupus erythematosus (SLE) have
clinical evidence of nephritis at the time of diagnosis, with an estimated total of 50–60 …

[HTML][HTML] Joint European League Against Rheumatism and European Renal Association–European Dialysis and Transplant Association (EULAR/ERA-EDTA) …

GK Bertsias, M Tektonidou, Z Amoura… - Annals of the …, 2012 - ard.bmj.com
Objectives To develop recommendations for the management of adult and paediatric lupus
nephritis (LN). Methods The available evidence was systematically reviewed using the …

Safety and efficacy of long‐term Voclosporin treatment for lupus nephritis in the phase 3 AURORA 2 clinical trial

A Saxena, EM Ginzler, K Gibson… - Arthritis & …, 2024 - Wiley Online Library
Objective AURORA 2 evaluated the long‐term safety, tolerability, and efficacy of voclosporin
compared to placebo in patients with lupus nephritis (LN) receiving an additional two years …

Mycophenolate mofetil versus cyclophosphamide for induction treatment of lupus nephritis

GB Appel, G Contreras, MA Dooley… - Journal of the …, 2009 - journals.lww.com
Recent studies have suggested that mycophenolate mofetil (MMF) may offer advantages
over intravenous cyclophosphamide (IVC) for the treatment of lupus nephritis, but these …

Mycophenolate mofetil or intravenous cyclophosphamide for lupus nephritis

EM Ginzler, MA Dooley, C Aranow… - … England Journal of …, 2005 - Mass Medical Soc
Background Since anecdotal series and small, prospective, controlled trials suggest that
mycophenolate mofetil may be effective for treating lupus nephritis, larger trials are …

EULAR recommendations for the management of systemic lupus erythematosus. Report of a Task Force of the EULAR Standing Committee for International Clinical …

GK Bertsias, JPA Ioannidis, J Boletis… - Annals of the …, 2008 - ard.bmj.com
Objective: Systemic lupus erythematosus (SLE) is a complex disease with variable
presentations, course and prognosis. We sought to develop evidence-based …